SCID mouse

SCID mouse,

(severe combined immunodeficiency) a strain of mice lacking in T and B lymphocytes and immunoglobulins, either from inbreeding with an autosomal-recessive trait or from genetic engineering, used as a model for studies of the immune system.

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mouse [mows]

a small rodent, various species of which are used in laboratory experiments.

1. a small loose body.

2. a computer pointing device.

joint mouse a movable fragment of synovial membrane, cartilage, or other body within a joint; usually associated with degenerative osteoarthritis and osteochondritis dissecans.

knockout mouse a mouse that has had a specific gene artificially deleted from its genome.

nude mouse a mouse homozygous for the nu gene; these mice are hairless, lack a thymus, and thus lack T lymphocytes.

peritoneal mouse a free body in the peritoneal cavity, probably a small detached mass or omentum, sometimes visible radiographically.

SCID mouse (severe combined immunodeficiency) a strain of mice lacking in T and B lymphocytes and immunoglobulins, either from inbreeding with an autosomal recessive trait or from genetic engineering, used as a model for studies of the immune system.