CLEC11A

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CLEC11A

A gene on chromosome 19q13.3 that encodes a C-type lectin domain protein expressed in bone, cartilage and bone marrow, which stimulates the proliferation and differentiation of haematopoietic stem cells. CLEC11A acts synergistically with other cytokines, such as IL3, GCSF, GMCSF and FLT3 ligand. CLEC11A suppresses SCF-stimulated erythrocyte proliferation.
References in periodicals archive ?
Click here to view the complete list of 2009 SCGF projects.
SyStemix intends to continue the project and the two companies plan to explore the potential of a new SCGF project collaboration under new contract terms.
The potential applications of the SCGF would initially be in chemotherapy, radiation treatment and bone marrow transplantation.