S1PR4

S1PR4

A gene on chromosome 19p13.3 that encodes an EDG (endothelial differentiation, G protein-coupled) family receptor for sphingosine 1-phosphate, a bioactive lysophospholipid that regulates cell proliferation, apoptosis, motility and neurite retraction. It acts intracellularly as a second messenger and extracellularly as a receptor ligand, and it elicits diverse physiologic effects on most types of cells and tissues.
References in periodicals archive ?
Source:RefSeq mRNA;Acc:NM_214034] ENSSSCG00000013 474 S1PR4 sphingosine-1-phosphate receptor 4 [Source:HGNC Symbol;Acc:3170] ENSSSCG00000022 289 PCDH1 protocadherin 1 [Source:HGNC Symbol;Acc:8655] ENSSSCG00000014 427 FBXO38 F-box protein 38 [Source:HGNC Symbol;Acc:28844] ENSSSCG00000007 541 PDGFA platelet-derived growth factor alpha polypeptide [Source:HGNC Symbol;Acc:8799] ENSSSCG00000007 580 WIPI2 Sus scrofa WD repeat domain, phosphoinositide interacting 2 (WIPI2), mRNA.