S100A3

S100A3

A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which have 2 EF-hand calcium-binding motifs. S100 proteins are localised in the cytoplasm and/or nucleus of a wide range of cells; they are involved in regulating cell cycle progression and differentiation and other intracellular activities. The S100A3-encoded protein is highly expressed in skin and may be involved in calcium-dependent differentiation of skin and hair shaft.
References in periodicals archive ?
Aberrantly differentiated cells in benign pilomatrixoma reflect the normal hair follicle: immunohistochemical analysis of Ca-binding S100A2, S100A3 and S100A6 proteins.
D, Ichiro Sasaki, Masahito Yamaguchi and Kenji Kizawa for their paper, "Elution of S100A3 from hair fiber: new model for hair damage emphasizing the loss of S100A3 from cuticle;"