S100A7

(redirected from S100 calcium-binding protein A7)

S100A7

A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which have 2 EF-hand calcium-binding motifs. S100 proteins are localised in the cytoplasm and/or nucleus of a wide range of cells; they are involved in regulating cell cycle progression and differentiation and other intracellular activities. The function of the  S100A7-encoded protein is unknown.
 
Molecular pathology
S100A7 is overexpressed in the skin lesions of psoriasis, but is not a candidate gene for familial psoriasis.
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At seven o'clock, the four members ascended to the clubroom, tied their badges round their heads, and took their seats with great solemnity.
A silence of a minute succeeded, during which the Indian sat mute; then, full of the dignity of his office, he commenced his brief tale, with a solemnity that served to heighten its appearance of truth.
And, therefore, since we have been unfortunate enough to introduce our heroine at so inauspicious a juncture, we would entreat for a mood of due solemnity in the spectators of her fate.
In either case, there was very much the same solemnity of demeanour on the part of the spectators, as befitted a people among whom religion and law were almost identical, and in whose character both were so thoroughly interfused, that the mildest and severest acts of public discipline were alike made venerable and awful.
She waited for us, not herself taking a step, and I was conscious of the rare solemnity with which we presently approached her.
Affected by the solemnity of the scene, there was a wondering gaze of incredulous curiosity in his countenance.
The older people have dances from home, strange and complicated steps which they execute with grave solemnity.
Do I seem to have lost my solemnity, my gravity, my poise, my dignity?
The solemnity is simple; the five corps assemble at night, and at a signal they all fall loading themselves with beer, out of pint-mugs, as fast as possible, and each man keeps his own count--usually by laying aside a lucifer match for each mud he empties.
The boys talked little, and only under their breath, for the time and the place and the pervading solemnity and silence oppressed their spirits.
No one who is unfamiliar with life in rural neighborhoods can imagine the gravity, the importance, the solemnity of this last day of school.
He told me, with great solemnity, I must go back to Covey; but that before I went, I must go with him into another part of the woods, where there was a certain ~root,~ which, if I would take some of it with me, carrying it ~always on my right side,~ would render it impos- sible for Mr.