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Sézary syndrome

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Sézary syndrome
A leukemic phase of CTCL that develops in some patients, characterized by the appearance of malignant T cells in the peripheral blood and sometimes in the lymph nodes. The syndrome is named for Alfred Sézary (1880–1956), a French dermatologist.
Mentioned in: Cutaneous T-Cell Lymphoma
Sézary syndrome
an exfoliative erythroderma due to cutaneous infiltration of reticular lymphocytes, with alopecia, edema and hyperkeratosis; believed to be a variant of mycosis fungoides. This condition of humans is similar to the epidermotropic form of cutaneous lymphoma which occurs in dogs. The Sézary cell is a characteristic cerebriform lymphocyte which occurs in the dermis and blood of patients with Sézary syndrome. It has a distinctive markedly convoluted nuclear membrane.


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