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propafenone
(redirected from Rythmol sr)

   Also found in: Wikipedia 0.01 sec.
propafenone /pro·pa·fe·none/ (pro″pah-fe´nōn) a sodium channel blocking agent acting on the Purkinje fibers and the myocardium; used as the hydrochloride salt as an antiarrhythmic.
propafenone [pro″pah-fe´nōn]
a sodium channel blocking agent that acts on the Purkinje fibers and the myocardium; used as the hydrochloride salt in treatment of life-threatening arrhythmias, administered orally.

propafenone (prō´pfē´nōn),
n brand name: Rythmol;
drug class: antidysrhythmic (Class IC);
action: able to slow conduction velocity; reduces cardiac muscle membrane responsiveness; inhibits automaticity; increases ratio of effective refractory period to action potential duration; β-blocking activity;
use: documented life-threatening dysrhythmias.

propafenone
Rythmol® Cardiology A beta-blocking antiarrhythmic for severe ventricular and supraventricular arrhythmias–A Fib, V Tach, conduction block, HTN Complications Ventricular proarrhythmia; conduction defects Adverse effects Neurologic–headache, dizziness, paresthesias, peripheral neuropathy, GI–eg, N&V, anorexia. See Antiarrhythmic, Beta-blockers.


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for infringement of United States Patent 5,681,588, which expires in 2014 and relates to Reliant's Rythmol SR product.
DDMAC reviewed two of Reliant's promotional pieces, identified as RYTH-2026 and RYTH-1028, for Rythmol SR (propafenone HCl) extended-release capsules and determined the promotional pieces to be false and misleading because they failed to communicate serious risk information for Rythmol SR but broadened the indication for the product.
Angotti led the expansion of a mass market and specialty sales force in the United States to promote both Lovaza, a treatment for hypertriglyceridemia, and Rythmol SR, a treatment for atrial fibrillation.
 
 
 
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