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arthritis
(redirected from Rueumatiod arthritis)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.02 sec.
arthritis /ar·thri·tis/ (ahr-thri´tis) pl. arthri´tides   inflammation of a joint.
acute arthritis  arthritis marked by pain, heat, redness, and swelling.
chronic inflammatory arthritis  inflammation of joints in chronic disorders such as rheumatoid arthritis.
arthritis defor´mans  severe destruction of joints, seen in disorders such as rheumatoid arthritis.
degenerative arthritis  osteoarthritis.
enteropathic arthritis  arthritis associated with inflammatory bowel disease or following bacterial infection of the bowel.
hypertrophic arthritis  osteoarthritis.
infectious arthritis  arthritis caused by bacteria, rickettsiae, mycoplasmas, viruses, fungi, or parasites.
juvenile rheumatoid arthritis  rheumatoid arthritis in children, with swelling, tenderness, and pain involving one or more joints, sometimes leading to impaired growth and development, limitation of movement, and ankylosis and flexion contractures of the joints; often accompanied by systemic manifestations.
Lyme arthritis  see under disease.
menopausal arthritis  that seen in some menopausal women, due to ovarian hormonal deficiency, and marked by pain in the small joints, shoulders, elbows, or knees.
arthritis mu´tilans  severe deforming polyarthritis with gross bone and cartilage destruction, an atypical variant of rheumatoid arthritis.
rheumatoid arthritis  a chronic systemic disease primarily of the joints, usually polyarticular, marked by inflammatory changes in the synovial membranes and articular structures and by atrophy and rarefaction of the bones. In late stages, deformity and ankylosis develop.
septic arthritis , suppurative arthritis a form marked by purulent joint infiltration, chiefly due to bacterial infection but also seen in Reiter's disease.
tuberculous arthritis  that secondary to tuberculosis, usually affecting a single joint, marked by chronic inflammation with effusion and destruction of contiguous bone.

ar·thri·tis (är-thrts)
n. pl. ar·thrit·i·des (-thrt-dz)
Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes.

ar·thritic (-thrtk) adj. & n.
ar·thriti·cal·ly adv.
click for a larger image
arthritis
Top: normal finger joint
Bottom: arthritic finger joint

Arthritis
Inflammation of a joint that may lead to changes in the joint's structure. It causes pain and swelling. Rheumatoid arthritis is a chronic disease that leads to crippling deformities.

arthritis
[ärthrī′tis]
Etymology: Gk, arthron, joint, itis
any inflammatory condition of the joints, characterized by pain, swelling, heat, redness, and limitation of movement. See also osteoarthritis, rheumatoid arthritis.

arthritis [ahr-thri´tis] (pl. arthri´tides)
inflammation of a joint. adj., adj arthrit´ic. The term is often used by the public to indicate any disease involving pain or stiffness of the musculoskeletal system. Arthritis is not a single disease, but a group of over 100 diseases that cause pain and limit movement. The most common types are osteoarthritis and rheumatoid arthritis.
 Arthritis of the fingers. Left, normal hand and finger. Right, arthritic hand and finger, with ankylosis, or “locking” of the joint by bone and scar tissue. Courtesy of Bergman Associates.
acute arthritis arthritis marked by pain, heat, redness, and swelling.
acute rheumatic arthritis swelling, tenderness, and redness of many joints of the body, accompanying rheumatic fever.
hypertrophic arthritis rheumatoid arthritis marked by hypertrophy of the cartilage at the edge of the joints; osteoarthritis.
juvenile rheumatoid arthritis rheumatoid arthritis in children under age 16, characterized by swelling, tenderness, and pain, involving one joint or several joints and lasting more than six weeks. It may lead to impaired growth and development, limitation of movement, and ankylosis and contractures of joints. At times it is accompanied by systemic manifestations such as spiking fever, transient rash on the trunk and limbs, hepatosplenomegaly, generalized lymphadenopathy, and anemia, in which case it is known as Still's disease or systemic onset juvenile rheumatoid arthritis.
Lyme arthritis Lyme disease.
psoriatic arthritis that associated with severe psoriasis, classically affecting the terminal interphalangeal joints.
rheumatoid arthritis a chronic systemic disease characterized by inflammatory changes occurring throughout the body's connective tissues. As such, it is classified as a collagen disease. This form of arthritis strikes during the most productive years of adulthood, with onset in the majority of cases between the ages of 20 and 40. No age is spared, however, and the disease may affect infants as well as the very old. The disease affects men and women about equally in number, but three times as many women as men develop symptoms severe enough to require medical attention.
Etiology. The cause of rheumatoid arthritis is unknown and it is doubtful that there is one specific cause. It is regarded by some researchers as an autoimmune disease, in which the body produces abnormal antibodies against its own cells and tissues. Evidence to support this theory is found in the fact that there is an abnormally high level of certain types of immunoglobulins in the blood of patients suffering from rheumatoid arthritis. Other researchers contend that the disease may be due to infection, perhaps from an undefined virus or some other microorganism (e.g., Mycoplasma). There also is the possibility that rheumatoid arthritis is a genetic disorder in which one inherits a predisposition to the disease. Physical and emotional stress also play some part in the onset of acute attacks; however, psychological stress is implicated as a causative factor in the onset of many illnesses.
Symptoms and Pathology. In about 75 per cent of patients the onset of rheumatoid arthritis is gradual, with only mild symptoms at the beginning. Early symptoms include malaise, fever, weight loss, and morning stiffness of the joints. One or more joints may become swollen, painful, and inflamed. Some patients may experience only mild episodes of acute symptoms with lengthy remissions. The more typical patient, however, experiences increasingly severe and frequent attacks with subsequent joint damage and deformity. The pattern of remissions and exacerbations continues throughout the course of the disease.

If untreated, and sometimes in spite of treatment, the joint pathology goes through four stages: (1) proliferative inflammation of the synovium with increased exudate, which eventually leads to thickening of the synovium; (2) formation of a layer of granulation tissue (pannus) that erodes and destroys the cartilage and eventually spreads to contiguous areas, causing destruction of the bone capsule and parts of the muscles that control the joint; (3) fibrous ankylosis resulting from invasion of the pannus by tough fibrous tissue; and (4) bony ankylosis as the fibrous tissue becomes calcified.

In addition to the joint changes there is atrophy of muscles, bones, and skin adjacent to the affected joint. The most characteristic lesions of rheumatoid arthritis are subcutaneous nodules, which may be present for weeks or months and are most commonly found over bony prominences, especially near the elbow.

Because rheumatoid arthritis is a systemic disease, there is involvement of connective tissues other than those in the musculoskeletal system. Degenerative lesions may be found in the collagen in the lungs, heart, blood vessels, and pleura.

Patients with rheumatoid arthritis appear undernourished and chronically ill. Most are anemic because of the effect of the disease on blood-forming organs. The erythrocyte sedimentation rate is elevated and the WBC may be slightly elevated.
Treatment and Patient Care. Management of rheumatoid arthritis is aimed at providing rest and freedom from pain, minimizing emotional stress, preventing or correcting deformities, and maintaining or restoring function so that the patient can enjoy as much independence and mobility as possible. Occupational therapy is needed to teach patients effective ways to carry out such activities of daily living as grooming and self-care, preparing meals, and light housekeeping. This often involves using specially designed utensils and tools that allow deformed joints to perform these tasks.
Rest and Exercise. It is recommended that the patient with rheumatoid arthritis plan for 10 to 12 hours of sleep out of each 24. The patient should be careful to maintain good posture while lying in bed and avoid pillows or other devices that support the joints in a flexed position. A firm mattress is recommended, with only one pillow under the head. During periods of severe attacks, the patient may require continuous bed rest.

The purpose of rest is to allow the body's natural defenses against inflammation to work at optimal level. It is necessary, however, even in the acute phase to balance rest with prescribed exercises which take into account the severity of the case, the joints affected, and the patient's individual needs and tolerance.
Physical Therapy. The goals of physical therapy for the patient with rheumatoid arthritis are to prevent and correct deformities, control pain, strengthen weakened muscles, and improve function.

Therapeutic exercise is of major importance in the physical therapy program established for the patient. It is necessary to enlist the patient's cooperation, and this can be done most effectively by explaining the purposes of the exercises and teaching ways to exercise that will not increase pain. In many instances proper exercise can actually diminish pain. The patient's tolerance for exercise must be carefully monitored. While it is expected that some discomfort may be present during exercise, there should not be persistent pain that continues for hours after the exercises have been done. If such pain and fatigue do occur, the exercise program should be reviewed and revised so that a good balance of rest and exercise is obtained. It should be remembered that overactivity can contribute to the inflammatory process.

Applications of heat or cold may be used in the management of rheumatoid arthritis. Heat applications improve circulation, promote relaxation, and relieve pain. When used in conjunction with exercise, heat can allow more freedom of joint movement. Various forms of heat therapy may be used, including dry heat, moist heat, diathermy, and ultrasound. For dry heat a therapeutic infrared heat lamp may be most convenient during home care. Hot water bottles or electric heating pads also may be used. For treatment of the hands, paraffin baths are effective. Wet heat can be applied by hot tub baths with the water temperature not exceeding 39°C (102°F) or by means of a towel dipped in hot water, wrung out, and applied to the joint. Whirlpool baths are effective, especially when prolonged treatment is indicated. Relief from pain and stiffness can be provided for some patients by applications of cold packs to the affected joints. This can be done by placing ice packs directly over the joint. When either heat or cold is used, care must be taken to protect the patient's skin. It should be remembered that rheumatoid arthritis affects the skin as well as other tissues.

Whenever it is necessary to handle the joints and limbs of a patient with rheumatoid arthritis, it is extremely important to move slowly and gently, avoiding sudden, jarring movements which stimulate muscle contraction and produce pain. The affected joints should be supported so that there is no excessive motion.
Medication. There is no drug that will cure arthritis. The health care provider does have a variety of medications that may be prescribed, depending on the needs and tolerance of the patient. It is important that the patient be advised of the expected results and possible undesirable side effects that may accompany ingestion of certain drugs. He or she should also be advised that therapeutic trials of several different drugs may be necessary. With this information at hand, he or she can work cooperatively with the physician in determining which drug or drugs can be most beneficial for treatment of the condition.

Aspirin was among the first drugs used to treat rheumatoid arthritis and remains a low-cost treatment option. It is a potent antiinflammatory agent when given at dosages that achieve a serum level of 20–30 mg/100 ml. For those prone to stomach upset or other gastrointestinal side effects from aspirin, enteric-coated tablets or antacid mixtures of aspirin are available.

Other nonaspirin, nonsteroidal antiinflammatory drugs (NSAIDs) include the indole derivatives indomethacin, sulindac, and tolmetin and the phenylalkanoic acid derivatives fenoprofen, ibuprofen, and naproxen. Nowadays NSAIDs are the most used group of medications for treatment of arthritis. They may provide more relief than aspirin for certain patients, but they also may have side effects related to the gastrointestinal and nervous systems. COX-2 (cyclooxygenase-2) inhibitors are the latest class of NSAIDs. They have fewer gastrointestinal side effects than other NSAIDs.

Cytotoxic agents may also be used; these drugs act as immunosuppressants and block the inflammatory process of the disease. methotrexate is the most common of these. The dosage for the management of rheumatoid arthritis is much lower than the dosages for malignancies; thus the associated side effects are fewer. gold compounds or penicillamine may be prescribed for selected patients who cannot tolerate or are not responding well to more conservative methods of treatment.

The corticosteroids may be used in treating rheumatoid arthritis, but they are not a substitute for other forms of treatment. In some cases these drugs produce side effects that are more difficult to treat than arthritis. They also may worsen certain features of the disease rather than relieve them. Drugs included in this group are cortisone, hydrocortisone, prednisone, prednisolone, and dexamethasone.

Another group of medications that reduce inflammation are the biological response modifiers. Members of this group used to treat arthritis include etanercept and infliximab.
Surgical Intervention and Orthopedic Devices. In the past, surgical intervention was reserved for patients who had already suffered severe joint deformity. There is presently a trend toward the use of surgery in the early stages of the disease so that deformities and serious mechanical abnormalities can be prevented or at least modified.

One surgical procedure employed is synovectomy (excision of the synovial membrane of a joint). The goal of this treatment is to interrupt the destructive inflammatory processes that eventually lead to ankylosis and invasion of surrounding cartilage and bone tissues.

Surgical repair of a hip joint (arthroplasty) may be performed when there is extensive damage and ambulation is not possible. The purpose of this procedure is to restore, improve, or maintain joint function. In cases in which it is not possible to restore the damaged hip joint there is a surgical procedure in which the diseased joint is completely replaced with a total hip prosthesis. The procedure is called a total hip replacement. A similar procedure involving total replacement of the knee can be done when there is extensive damage to the knee joint.

Braces, casts, or splints are sometimes used to immobilize the affected part so that it can rest during an active stage of the disease. Devices that immobilize the affected joint also may allow for motion of adjacent muscle, thereby improving muscle strength and permitting more independence on the part of the patient. Braces also may be used to prevent deformities by maintaining good position of the joints.
Patient Education. Unfortunately, arthritis is so widespread and such a crippling disease that its victims may be easy prey for charlatans and promoters of “miraculous cures.” The nature of the disease, with its unexplained remissions and relief of symptoms, makes it easy for unscrupulous individuals to convince the arthritic patient that some bizarre treatment they have used has indeed “cured” the arthritis. It is important that members of the health team recognize the need for patient education and work diligently with the patient and family so that they can cooperatively participate in a program of care that is most effective for the individual patient.

Home care is an essential part of the management of arthritis. To help in education of the public The Arthritis Foundation provides a number of pamphlets and other educational materials, supports a broad program of research and education, and helps finance improvement of local facilities for treatment of arthritis. The address of the foundation is The Arthritis Foundation, 1330 W. Peachtree St., Atlanta, GA 30309, telephone 404-872-7100.
suppurative arthritis inflammation of a joint with a purulent effusion into the joint, due chiefly to bacterial infection.
systemic onset juvenile rheumatoid arthritis Still's disease.

arthritis,
n a condition characterized by inflammation of the joints.
arthritis, degenerative,
n painful joint disease marked by lack of mobility caused by degeneration of the articular cartilage.
arthritis, inflammatory,
n disease marked by swollen joints, often painful; may be the result of trauma, infection, metabolic disturbances, or other causes.

arthritis (ärthrī´tis),
n any of a number of types of inflammation of a joint or joints.
arthritis, allergic,
n an arthralgia, swelling, and stiffness of joints associated with food and drug allergies and serum sickness.
arthritis, atrophic,
n See arthritis, rheumatoid.
arthritis, bacterial,
n See arthritis, infective.
arthritis, hypertrophic
arthritis, infective,
n (bacterial arthritis), a primary and secondary bacterial infection of the joints (e.g., by staphylococcal, gonococcal, streptococcal, or pneumococcal organisms).
arthritis, rheumatic
n an acute polyarticular and migratory arthritis of unknown cause but assumed to be related to group A streptococcal infection of the upper respiratory tract.
arthritis, rheumatoid
n a chronic destructive inflammation of the joints due to an autoimmunity with unknown etiology, with associated systemic manifestations such as weakness, weight loss, anemia, leukopenia, splenomegaly, lymphadenopathy, and the formation of subcutaneous nodules. Chronic synovitis and regressive changes in the articular cartilage occur with pain, swelling, deformity, limitation of motion, and occasionally ankylosis of the joints. Small joints are principally affected, with onset in the third or fourth decade of life.
arthritis, senile,
n an arthritis occurring in persons of advanced age.
arthritis, specific infectious,
n an arthritis caused by direct invasion and subsequent infection of joint structures by microorganisms from the bloodstream. Nearly all pathogenic bacteria have been isolated as etiologic agents.
arthritis, traumatic,
n an acute or chronic inflammation of a joint as a result of acute or chronic injury.
Arthrobacter,
n a genus of a strictly aerobic gram-positive bacteria found in soil and present in dental caries.

arthritis
inflammation of a joint. See also arthropathy, polyarthritis.

bacterial arthritis
arises from penetrating wounds, extension from adjacent tissues or by hematogenous spread, especially umbilical infection in the newborn. More common in farm animals than dogs and cats. Some specific causes are erysipelas in pigs and sheep, Streptococcus spp. in pigs, calves and lambs, coliforms in calves, Haemophilus spp. in pigs (Glasser's disease) and lambs, Arcanobacterium spp. in lambs, and Chlamydophila pecorum in calves and lambs.
corynebacterial arthritis
a nonsuppurative arthritis and bursitis of lambs caused by Corynebacterium pseudotuberculosis.
crystal-induced arthritis
deforming arthritis
see erosive arthritis (below).
degenerative arthritis
see degenerative joint disease.
drug-induced arthritis
a number of antibiotics, particularly sulfonamide-trimethoprin, may cause an immune-mediated arthritis and other clinical signs, including glomerulonephritis, polymyositis and thrombocytopenia.
enteropathic arthritis
arthritis of unknown etiology, but associated with bowel disease such as ulcerative colitis and regional enteritis in humans. A similar condition has been recognized in dogs.
erosive arthritis
characterized by the erosion of articular cartilage and destruction of subchondral bone which is dramatically demonstrated radiographically. Generally these are the immune-mediated joint diseases and include canine rheumatoid arthritis (below), polyarthritis in Greyhounds, feline chronic progressive polyarthritis. Called also deforming arthritis.
erysipelas arthritis
occurs sporadically in calves, more commonly in lambs and as a major disease in pigs. In all species it is an acute or chronic, nonsuppurative arthritis.
fibrinous arthritis
the acute inflammatory stage of most infectious arthritides. The joint fluid is increased in volume and is turbid and mucinous, the fibrin appearing as a particulate deposit on the serous surface.
idiopathic nondeforming arthritis
occurs in dogs and uncommonly in cats in the absence of systemic lupus erythematosus or chronic infectious systemic disease. It may involve one or several joints with fever, lameness and muscle atrophy. The disease may be chronic and cyclic with spontaneous remissions and recurrences. Presumed to be immune-mediated.
immune-mediated arthritis
noninfectious joint disease involving immune mechanisms. Seen mainly in dogs and cats. See also nonerosive arthritis (below).
infectious arthritis
may be caused by bacteria, mycoplasma, virus, fungus, rickettsiae, or protozoa in the joint only or as part of systemic infection.
lymphocytic-plasmacytic arthritis
see lymphocytic-plasmacytic synovitis.
mycoplasma arthritis
Mycoplasma hyosynoviae and M. hyorhinis cause arthritis in pigs, the former with an accompanying polyserositis.
neonatal arthritis
localization from a systemic infection in the joints causing septic arthritis, often in several joints, and infection in other vulnerable organs. Neonatal susceptibility is due to availability of the umbilical vessels as a port of entry and an inadequate defense until maternal antibodies provide passive immunity. Called also navel ill, omphalitis.
nonerosive arthritis
includes those without significant radiographic changes. Includes the arthritis that occurs in association with canine systemic lupus erythematosus and chronic systemic infections, enteropathic arthritis and idiopathic nondeforming arthritis.
persistent proliferative arthritis
see periosteal proliferative polyarthritis.
retroviral arthritis
the arthritis of goats caused by a retrovirus. The syndrome also includes encephalitis and pneumonia. Called also big-knee. See also caprine arthritis-encephalitis.
rheumatoid arthritis (RA)
a chronic, autoimmune disease of dogs that causes swelling and lameness in joints, often accompanied by systemic signs of fever, malaise and lymphadenopathy. The erosive, destructive changes in joints can be demonstrated on x-rays. The disease is similar to that described in humans and the diagnosis is usually based on satisfying criteria used for humans.
septic arthritis
acute arthritis due to infection of a kind likely to establish a bacteremia or septicemia.
traumatic arthritis
may be caused by trauma that penetrates the joint capsule, introducing infectious agents and resulting in an infectious arthritis, or injures articular cartilage or soft tissues supporting the joint.

arthritis
Inflammation of joints of which there are ±100 clinical forms Etiology Infectious, autoimmune, idiopathic, metabolic, traumatic Clinical Stiffness, warmth, swelling, redness, pain. See Acne arthritis, Ankylosing spondylitis, Bacterial arthritis, Degenerative arthritis, Familial histiocytic dermatoarthritis arthritis, Gonococcal arthritis, Gouty arthritis, Lupus erythematosus, Lyme arthritis, Osteoarthritis, Pseudogout, Rheumatoid arthritis, Sexually acquired reactive arthritis, Systemic-onset juvenile rheumatoid arthritis, Tuberculous arthritis, Viral arthritis.

Patient discussion about arthritis.

Q. can you get rid of arthritis medications? Or are these pills addictive or will make me dependant on them?

A. There are over a 100 drugs, medications and medicines used in the treatment of arthritis. you'll have to be more specific.

Q. What are the symptoms of arthritis? My ankles are swollen and hurt. Is this Arthritis? What are the symptoms for Arthritis?

A. Because there are over 100 different types of arthritis, symptoms of the disease can be variable, but there are certain signs which point to the disease.
Persistent joint pain.

Pain or tenderness in a joint which is aggravated by movement or activity, such as walking, getting up from a chair, writing, typing, holding an object, throwing a ball, turning a key.

Inflammation indicated by joint swelling, stiffness, redness, and/or warmth.
Inflammation: The Battle Within

Joint deformity.
Arthritis Hand Gallery

Loss of range of motion or flexibility in a joint.
What Is Range Of Motion?

Unexplained weight loss.
Full article:
http://arthritis.about.com/cs/arthgen/ht/arthritissigns.htm

Useful:
http://www.webmd.com/solutions/hs/arthritis/symptoms
http://www.arthritis.org/

Hope this helps.

Q. How can I treat Arthritis pain? Anyone have tips for relieving arthritis pain?

A. Can you please tell us more about this healthy chocolate that eliminates the pain?

Read more or ask a question about arthritis


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