The pharmacokinetic parameters for both routes of administration
were similar, with a mean peak plasma concentration ([C.
With FDA approval, Gamunex-C becomes the first and only immunoglobulin therapy approved in the US with both intravenous and subcutaneous routes of administration
to treat PI.
Changes in this edition of the long-established reference (since 1946) include route-specific monographs for drugs that are available in different routes of administration
Peplin's earlier stage pipeline is targeted at other forms of cancer using topical, intralesional and systemic routes of administration
This newly redesigned edition describes hardcore drug-abusing populations, emerging drugs and markets, new routes of administration
, use patterns, demand for treatment, drug-related criminal activity, and supply and distribution patterns from midyear 1999 to midyear 2000.
Concludes Siegel, "The history of coca and cocaine [use] has been a history of increasing doses, increasingly effective routes of administration
and an increasing incidence of dependence and toxicity.
However, with the entrance of vaccines with novel routes of administration
, such as AstraZeneca's intranasal FluMist and Sanofi's Fluzone IntraDermal, GlobalData projects a dramatic shift favoring the adoption of such vaccines over the traditional intramuscular vaccines.
The company also is developing its calcium phosphate nanotechnology (CaP) for novel vaccines, including hepatitis B, avian flu and biodefense vaccines for toxins such as anthrax, as well as a system for delivering drugs via alternative routes of administration
These porous microparticle formulations have tightly controlled size distributions, and can allow drugs to be released over periods of time ranging from days to weeks by intravenous, inhalation, subcutaneous, or oral routes of administration
In a series of four human clinical trials involving 128 subjects, AVI showed inhibition of CYP3A4 using doses of AVI-4557 ranging from 10 mg to 300 mg as either single or repeated daily doses by intravenous, subcutaneous or oral routes of administration
At the same time, the convergence of socioeconomic and technology factors is driving interest in pulmonary drug delivery technology and devices as an alternative to oral and parenteral routes of administration
for systemic drugs.
Applications of HMD using oral, IV, and other routes of administration