route of administration

(redirected from Routes of administration)

route of administration

[ro̅o̅t, rout]
Etymology: Fr, route, course; L, administrare, to serve
(of a drug) any one of the body systems in which a drug may be administered, such as intradermally, intrathecally, intramuscularly, intranasally, intravenously, orally, rectally, subcutaneously, sublingually, topically, or vaginally. Some medications can be given by only one route because absorption or maximum effectiveness occurs by that route only or because the specific substance is toxic or damaging when given by another route.

route of administration,

n the path by which a substance is taken into the body (i.e., by mouth, injection, inhalation, rectum, or by application). See also dosage form.
References in periodicals archive ?
The pharmacokinetic parameters for both routes of administration were similar, with a mean peak plasma concentration ([C.
With FDA approval, Gamunex-C becomes the first and only immunoglobulin therapy approved in the US with both intravenous and subcutaneous routes of administration to treat PI.
Changes in this edition of the long-established reference (since 1946) include route-specific monographs for drugs that are available in different routes of administration.
Peplin's earlier stage pipeline is targeted at other forms of cancer using topical, intralesional and systemic routes of administration.
This newly redesigned edition describes hardcore drug-abusing populations, emerging drugs and markets, new routes of administration, use patterns, demand for treatment, drug-related criminal activity, and supply and distribution patterns from midyear 1999 to midyear 2000.
Concludes Siegel, "The history of coca and cocaine [use] has been a history of increasing doses, increasingly effective routes of administration and an increasing incidence of dependence and toxicity.
However, with the entrance of vaccines with novel routes of administration, such as AstraZeneca's intranasal FluMist and Sanofi's Fluzone IntraDermal, GlobalData projects a dramatic shift favoring the adoption of such vaccines over the traditional intramuscular vaccines.
The company also is developing its calcium phosphate nanotechnology (CaP) for novel vaccines, including hepatitis B, avian flu and biodefense vaccines for toxins such as anthrax, as well as a system for delivering drugs via alternative routes of administration.
These porous microparticle formulations have tightly controlled size distributions, and can allow drugs to be released over periods of time ranging from days to weeks by intravenous, inhalation, subcutaneous, or oral routes of administration.
In a series of four human clinical trials involving 128 subjects, AVI showed inhibition of CYP3A4 using doses of AVI-4557 ranging from 10 mg to 300 mg as either single or repeated daily doses by intravenous, subcutaneous or oral routes of administration.
At the same time, the convergence of socioeconomic and technology factors is driving interest in pulmonary drug delivery technology and devices as an alternative to oral and parenteral routes of administration for systemic drugs.