Romano-Ward syndrome

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Romano-Ward syndrome

 [ro-mah´no ward´]
prolongation of the Q–T interval with syncope, sometimes with ventricular fibrillation and sudden death; it is inherited as an autosomal dominant trait and can be triggered by stress or exercise. See also long QT syndrome.

Ro·ma·no-Ward syn·drome

(rō-mahn'ō wărd), [MIM*192500]
a prolonged QT interval in the electrocardiogram in children subject to attacks of unconsciousness that result from ventricular arrhythmias including ventricular fibrillation; autosomal dominant inheritance, with one form caused by mutation in the potassium channel gene (KVLQT1) on chromosome 11 p. Compare: Jervell and Lange-Nielsen syndrome.

Romano-Ward syndrome

[rō·mä′nō wôrd]
Etymology: C. Romano, Italian physician, b. 1923; O.C. Ward, Irish physician, 20th century
an autosomal-dominant form of the long QT syndrome, characterized by syncope and sometimes ventricular fibrillation and sudden death. See also long QT syndrome.


C., Italian physician, 1923–.
Romano-Ward syndrome - a prolonged Q-T interval in the electrocardiogram in children subject to ventricular arrhythmias, including ventricular fibrillation. Synonym(s): Ward-Romano syndrome
Ward-Romano syndrome - Synonym(s): Romano-Ward syndrome


Owen C., 20th century Irish pediatrician.
Romano-Ward syndrome - see under Romano
Ward-Romano syndrome - Synonym(s): Romano-Ward syndrome
References in periodicals archive ?
Two inherited forms of LQTS with differing patterns of transmission have been described and include Romano-Ward syndrome (RWS)[5,6] and Jervell and Lange-Nielsen syndrome (JLNS).
Romano-Ward syndrome is the most common inherited form of LQTS and is transmitted as an autosomal-dominant trait[1,2.
A recessive variant of the Romano-Ward long-QT syndrome.
Romano-Ward long QT syndrome (RWLQTS): evidence of genetic heterogeneity.
Evidence of genetic heterogeneity in Romano-Ward long QT syndrome: analysis of 23 families.
channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias.