Rokitansky-Aschoff sinuses

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Ro·ki·tan·sky-Asch·off si·nus·es

(rō-ki-tahn'skē ahsh'of),
small outpocketings of the mucosa of the gallbladder which extend through the muscular layer; they may be congenital.


Karl Ludwig, German pathologist, 1866-1942.
Aschoff bodies - a form of granulomatous inflammation characteristically observed in acute rheumatic carditis. Synonym(s): Aschoff nodules
Aschoff cell - a large-cell component of rheumatic nodules in the myocardium.
Aschoff nodules - Synonym(s): Aschoff bodies
node of Aschoff and Tawara - a small node of modified cardiac muscle that gives rise to the atrioventricular bundle of the conduction system of the heart. Synonym(s): atrioventricular node; Tawara node
Rokitansky-Aschoff sinuses - see under Rokitansky


Karl Freiherr von, Austrian pathologist, 1804-1878.
Mayer-Rokitansky-Küster-Hauser syndrome - see under Mayer, Paul
Rokitansky disease - (1) Synonym(s): acute yellow atrophy of the liver - (2) Chiari syndrome
Rokitansky diverticulum
Rokitansky hernia - separation of the muscular fibers of the bowel allowing protrusion of a sac of the mucous membrane.
Rokitansky kidney
Rokitansky pelvis - Synonym(s): spondylolisthetic pelvis
Rokitansky tumor
Rokitansky-Aschoff sinuses - small outpocketings of the mucosa of the gallbladder which extend through the muscular layer.
Rokitansky-Küster-Hauser syndrome - Synonym(s): Mayer-Rokitansky-Küster-Hauser syndrome
References in periodicals archive ?
2] The pathogenesis of XGC is the rupture of Rokitansky-Aschoff sinuses and extravasation of bile into the muscular layer.
13] and Goodman and Ishaks have suggested that the important event is the extravasation of bile into the gall bladder wall, either from ruptured Rokitansky-Aschoff sinuses or focal mucosal ulceration.
The pathogenesis is thought to be related to extravasation of bile into the gallbladder wall from rupture of Rokitansky-Aschoff sinuses or by mucosal ulceration.
At this time, a repeat abdominal sonogram revealed a 4mm echogenic focus adherent to the anterior gallbladder wall with a comet tail sign, suggestive of cholesterol crystals lodged within Rokitansky-Aschoff sinuses of the gallbladder wall.
Adenomyomatosis represents the presence of intramural diverticula of the gallbladder mucosa, the Rokitansky-Aschoff sinuses, within a thickened, hypertrophied mucosa and muscularis propria of the gallbladder wall.
The "pearl necklace" sign was described when the Rokitansky-Aschoff sinuses within the thickened gallbladder wall filled with contrast and opacified during drip-infusion cholecystographic studies, giving a beaded necklace appearance (Figure 32).
This is followed by a downward progression of the lesion, possibly reaching the Rokitansky-Aschoff sinuses.
Extension of dysplasia into Rokitansky-Aschoff sinuses of the gallbladder or into peribiliary mucous glands can mimic invasive carcinoma.
A review of 40 cases of xanthogranulomatous cholecystitis suggests that the process in the gallbladder stems from an obstruction of the Rokitansky-Aschoff sinuses by inspissated bile followed by subsequent rupture and a xanthogranulomatous reaction.
1] It is mostly always linked with gallstones with pathogenesis being a mystery, trigger being gallstones, obstruction to bile flow and cholestasis and infection associated with ruptured Rokitansky-Aschoff sinuses (outpouchings of mucosal epithelium through gall bladder wall).
The gallbladder epithelium, which lines Rokitansky-Aschoff sinuses, enhances on the arterial phase, which results in cystic intramural collections with a thin rim of enhancement.
It is speculated that XGC may result from extravasation of bile into the gallbladder wall from rupture of occluded Rokitansky-Aschoff sinuses or through small ulceration in the mucosa.