Richter's syndrome

Richter's syndrome

an aggressive large cell lymphoma of humans, suggested to occur in animals.
References in periodicals archive ?
Richter's syndrome developing in a patient with adult onset Still's disease.
This is referred to as Richter's syndrome and occurs in about 5% of cases of CLL/SLL (1, 2).
announced today that the Company had initiated a Phase I/II trial of its anticancer agent CLORETAZINE(TM) (VNP40101M) as a single agent in refractory or relapsed chronic lymphocytic leukemia (CLL) and Richter's Syndrome.
The objectives of the trial are to: (i) determine the toxicities and maximum tolerated dose (MTD) of CLORETAZINE(TM) (VNP40101M) in patients with CLL or Richter's Syndrome who have failed a fludarabine-based regimen, and (ii) observe efficacy of CLORETAZINE(TM) (VNP40101M) given at the MTD in the same patient population.
Richter's syndrome (RS) refers to the occurrence of diffuse, large cell lymphomas in chronic lymphatic leukemia (CLL).
Malignant lymphoma supervening in chronic lymphocytic leukemia and related disorders, Richter's syndrome, a study of 25 cases.