ribonucleotide reductase

(redirected from Ribonucleotide reductases)

ri·bo·nu·cle·o·tide re·duc·tase

a protein complex that converts ribonucleotide diphosphates (NDPs) such as ADP and CDP to 2'-deoxyribonucleotide diphosphates (dNDPs) such as dADP and dCDP. This complex requires thioredoxin, thioredoxin reductase, and NADPH. It is crucial for DNA synthesis.

ribonucleotide reductase

(1) Ribonucleoside-diphosphate reductase, EC 1.17.4.1. 
(2) Ribonucleoside-triphosphate reductase, EC 1.17.4.2.
References in periodicals archive ?
Elledge also discovered a family of genes known as ribonucleotide reductases, which play a role in the synthesis of DNA and are switched on in response to DNA damage in yeast.
That enzyme, ribonucleotide reductase, converts the building blocks of RNA into the building blocks of DNA.
The modern forms of the ribonucleotide reductase probably evolved from some- thing similar to the P.