For example, in the rat, the misexpression of Hoxa1 leads to ectopic differentiation of vestibuloacoustic (VII) motor neuron in rhombomere
In the latter case, the presence of facial motoneurons in only one rhombomere
might represent a modification specific to amphibians.
Late effects of retinoic acid on neural crest and aspects of rhombomere
Cadherin-6 expression transiently delineates specific rhombomeres
, other neural tube subdivisions, and neural crest subpopulations in mouse embryos.
pattern the rhombomeres
and pharyngeal arches, or tissue primordia that
They migrate toward specific directions, sometimes traversing across brain compartments such as rhombomeres
(PN neurons and facial branchiomotor neurons) or pallium-subpallium boundaries (cortical interneurons).
Horigome, "Developmental morphology of branchiomeric nerves in a cat shark, Scyliorhinus torazame, with special reference to rhombomeres
, cephalic mesoderm, and distribution patterns of cephalic crest cells," Zoological Science, vol.
This bidirectional Eph/ ephrin signaling between cells is fundamentally involved in developmental processes that require organized patterning and movement of cells, such as axonal guidance, patterning of hindbrain rhombomeres
, and maintenance of cellular boundaries in the development of the central nervous system (3) or in the remodeling of blood vessels (4).
Developmental differences also exist for Abd motoneurons, as the abducens nucleus originates from embryonic rhombomeres
(Rhs) 5 and 6 for most vertebrates, including lampreys, teleosts, birds, and reptiles (1), and exclusively from Rhs 5 in frogs (16) and mammals (1).
This enhancer region has been shown to direct chick and mouse Hoxa2 gene expression in rhombomeres
3 and 5 of the hindbrain and the pharyngeal arches.
The vestibular nuclei arise from hindbrain rhombomeres
r1-r8, and the auditory nuclei arise exclusively from rhombomeres
The developing hindbrain of vertebrates contains a series of eight neuromeric units called rhombomeres