The decline during the forecast period can be attributed to the expected patent expiry of Astelin (azelastine hydrochloride), Nasonex (mometasone furoate), Nasacort AQ (triamcinolone acetonide) and Rhinocort
Aqua (budesonide) in the year 2011, 2014, 2016 (US) and 2017 respectively.
These include Zyrtec, a nonsedating antihistamine, and steroid aerosol nasal sprays such as Flonase and Rhinocort
, which prevent allergic reactions by coating nasal mucous membranes.
Upcoming patent expiries of note include: Advair (fluticasone and salmeterol), Nasonex (mometasone furoate monohydrate), Rhinocort
(budesonide), Symbicort (budesonide and formoterol inhalation), Singulair (montelukast) and Tracleer (bosentan).
A randomized, double-blind, placebo-controlled, three-way cross-over study was conducted in 108 SAR patients to compare the relative efficacy of Captisol-Enabled Budesonide + Azelastine Nasal Spray (Single Solution) and Rhinocort
Aqua([R])/ (Suspension) + Astelin([R]) Nasal Spray (Solution) against a placebo nasal spray solution in the treatment of allergic rhinitis in an environmental exposure chamber.
A Randomized, Double-Blind, Placebo-Controlled, Three-Way Cross-Over Study was conducted in 108 SAR patients to Compare the Relative Efficacy of Captisol-Enabled([R]) Budesonide + Azelastine Nasal Spray (Single Solution) and Rhinocort
Aqua (Suspension) + Astelin Nasal Spray (Solution) against Placebo Nasal Spray Solution in the Treatment of Allergic Rhinitis in an Environmental Exposure Chamber (EEC).
Harte-Hanks Direct won a Direct Marketing Association ECHO Leader Award for a Direct-to-Physician Campaign for AstraZeneca Rhinocort
Aqua called "The History of Allergies.
Table 19: Sales forecasts for Rhinocort
in allergic rhinitis in the US and five major EU markets ($ 000s), 2009-2019 100
Product Innovations/Introductions II-41 Aegis Therapeutics Develops ProTek[TM] II-41 Heel Launches Luffeel[R] in the US II-41 Palatin Technologies to Develop Bremelanotide II-41 Archimedes to Introduce Intranasal Formulation of Human Growth Hormone II-41 Sinofresh Launches SinoFresh[TM] Nasal & Sinus Care II-41 PARI Respiratory Launches Nasal Drug Delivery Program II-42 OptiNose to Develop New Range of Intranasal Products II-42 OptiNose and Cambridge Consultants to Develop Advanced Nasal Delivery Device II-42 Kurve Technology Develops ViaNase ID[TM] II-42 Upsher-Smith Introduces Fortical[R] Nasal Spray II-43 Schering-Plough Launches New Formulation of NASONEX[R] II-43 AstraZeneca Unveils Rhinocort
Aqua in the US II-43
Competing inhaled steroid products in this category include Nasonex[R] (Schering), Nasacort[R] (Aventis), Rhinocort
Aqua[R] (AstraZeneca) and Veramyst[R] (Glaxo).
His experience in successfully developing Rhinocort
Aqua and Pulmicort Turbuhaler (topical budesonide, the active ingredient in Entocort) while at Astra will be instrumental to us as we advance orBec(R) to Phase 3 completion in GI GVHD.
Health Responder Files and category samples include, but are not limited to: Back Pain Frequent Heartburn Enlarged Prostate Angina/Heart Disease Epilepsy Frequent Headaches Diabetes Blindness Osteoporosis Bleeding Gums Eczema/Psoriasis Alzheimer's Heart Condition Asthma Arthritis/Rheumatism Sports Injury Incontinence Adult and Childhood Allergies A sample of medications used by consumers in Health Responders: Advil Bayer Singulair Zantac Celebrex Flonase Aleve Excedrin Lipitor Benadryl Tavist Nasonex Anacin Pulmicort Paxil Sudafed Zyrtec Rhinocort
To date, more than 30 pharmaceutical spray drugs, including Flonase, FluMist, Rhinocort
Aqua and Proventil have been tested using ImageTherm's technology.