Rh system

Rh system

Transfusion medicine A family of blood group antigens that can cause fatal transfuion reactions if improperly matched Frequency of Rh antigens–whites Rh-e, 98%; Rh-D, 85%; Rh-c, 80%; Rh-C, 70%; Rh-E, 30%; Rh-D exposure is important in OB–an Rh-D-negative mother's anti-RH-D antibody is an IgG which may cross the placenta, and cause HDN–titer > 1:16 in the 8th month indicates maternal formation of alloantibodies, evidenced by stomatocytes in mom's blood; the Rh type is determined prenatally by PCR of amniotic cells Prophylaxis 300 µg of anti-D–RhoGAM neutralizes 30 ml feto-maternal hemorrhage containing 15 ml of Rh+ RBCs. See Blood group, Hemolytic disease of newborn, Rh immune globulin.
References in periodicals archive ?
Indeed, the Rh system has the most important antigen D structure and is the most widely used prior to transfusion (1), (2).
The Rh system is clinically as important as the ABO system because of its role in hemolytic diseases in newborns and in transfusion incompatibility (1).
The major antigens of the Rh system are encoded by RHD and RHCE genes on chromosome 1.
It is always important to know the genetic make-up of Rh system in a given geographical location.
It is very important to avoid Rh immunization due to blood transfusion because of strong antigenicity of Rh system.
To ensure RH remains within a given range, many companies install RH system alarms.
Perrault's professional publications reflect his significant research efforts into such areas as blood freezing, blood component therapy, antibody analysis, the Rh system, hepatitis, retroviruses and AIDS.
Reagents and card / cassette in amounts calculated on the amount of performed tests - Blood group (ABO and Rh system, immune antibodies in the test PTA) - 45 000 examinations for 3 years,- Newborn blood group (ABO and Rh system - 2serie, polyvalent serum BTA - 2 100 tests for 3 years,- Blood recipients blood group (ABO and Rh system, immune antibodies in the test PTA - 30 600 tests for 3 years,- Blood group donors and compatibility tests (checking the ABO and Rh group donor, proper attempt conformity) - 53 500 tests for 3 years,- Identification of antigen DVI direct agglutination test in newborns - 600 tests for 3 years.
Over 70 years ago, Ortho Products' research led to breakthroughs in understanding the Rh system in human blood.
The number of alleles in the ABO and Rh blood group systems, and the low antigenicity of all but the D antigen in the Rh system, make it relatively easy to supply blood in virtually unlimited quantities to patients requiring hemotherapy.
b) review or production of technical documentation for RH systems and components (including but not limited to): drawings, CAD models, technical specifications, safety evaluations, manufacturing sheets, analysis reports (operational, risk, integrated logistics or safety & hazard analysis);