Rh system

Rh system

Transfusion medicine A family of blood group antigens that can cause fatal transfuion reactions if improperly matched Frequency of Rh antigens–whites Rh-e, 98%; Rh-D, 85%; Rh-c, 80%; Rh-C, 70%; Rh-E, 30%; Rh-D exposure is important in OB–an Rh-D-negative mother's anti-RH-D antibody is an IgG which may cross the placenta, and cause HDN–titer > 1:16 in the 8th month indicates maternal formation of alloantibodies, evidenced by stomatocytes in mom's blood; the Rh type is determined prenatally by PCR of amniotic cells Prophylaxis 300 µg of anti-D–RhoGAM neutralizes 30 ml feto-maternal hemorrhage containing 15 ml of Rh+ RBCs. See Blood group, Hemolytic disease of newborn, Rh immune globulin.
References in periodicals archive ?
The two most important ones are ABO and the Rh system.
Indeed, the Rh system has the most important antigen D structure and is the most widely used prior to transfusion (1), (2).
The major antigens of the Rh system are encoded by RHD and RHCE genes on chromosome 1.
It is always important to know the genetic make-up of Rh system in a given geographical location.
To ensure RH remains within a given range, many companies install RH system alarms.
Perrault's professional publications reflect his significant research efforts into such areas as blood freezing, blood component therapy, antibody analysis, the Rh system, hepatitis, retroviruses and AIDS.
Over 70 years ago, Ortho Products' research led to breakthroughs in understanding the Rh system in human blood.
Tenders are invited for The Acquisition of Monoclonal Reagents for the Determination of Erythrocyte Antigens in Oab and Rh System
Rh system emerged as second most important blood group system due to hemolytic disease of newborn and its importance in Rh D-negative individuals in subsequent transfusions once they develop Rh antibodies.