The frequency of neonatal hemolytic disease and indirect hyperbilirubinemias related with Rh sensitization
has decreased with widespread use of anti-D gamma globulin, and the importance of minor blood group (subgroup) incompatibilities has gradually increased (1, 2).
The company collects high quality human blood plasma, the vital raw material that allows Kedrion Biopharma to produce and distribute plasma-derived therapeutic products for use in treating and/or preventing serious diseases and conditions such as hemophilia, primary immune system deficiencies and Rh sensitization
which can lead to hemolytic disease of the fetus and newborn.
The analyses were adjusted for maternal age, education and parity; smoking and alcohol use during pregnancy; gestational age; birth weight; and prenatal high-risk conditions (maternal anemia, intrapartum fever, preterm premature rupture of the membranes, excess amniotic fluid, diabetes, chronic hypertension, pregnancy-induced hypertension, renal disease, premature detachment of the placenta, placenta previa, bleeding of unknown cause, fetal growth restriction, Rh sensitization
, postterm pregnancy and history of delivering a preterm or small-for-gestational-age infant).
-- (HyperRHO[TM] S/D, Rho (D), Immune Globulin [Human]) and viral infections such as measles (rubeola)
The formation of Rh antibodies, known as Rh sensitization, has no immediate consequences.
To prevent Rh sensitization, physicians prescribe a dose of Rhophylac(R) to Rh-negative women between 28-30 weeks of pregnancy.