Rh immune globulin


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Related to Rh immune globulin: Rh incompatibility

Rh immune globulin

Rh immune globulin

RhIg, Rho(D) immune globulin Obstetrics A sterile plasma-based preparation rich in anti-Rh antibodies used to prevent production of Rho(D) antibodies in Rh-negative mothers who may have an Rh-positive infant; its use virtually eliminates HDN due to maternal Rh-antibody production. See Hemolytic disease of the newborn.

Rh immune globulin

A solution of gamma globulin containing anti-Rh; it is given to Rh-negative women at 28 weeks' gestation to minimize the potential for sensitization secondary to transplacental bleeding. The injection is repeated within 72 hr after delivery of an Rh-positive newborn if the mother's indirect and the newborn's direct Coombs tests are negative. The globulin also should be given to Rh-negative women after spontaneous or induced abortion. Previously called Rho(D) immune globulin.
See also: globulin
References in periodicals archive ?
Institutions were asked if Rh immune globulin is dispensed from the transfusion service, the pharmacy, or both.
Terms and policies related to the weak D phenotype and Rh immune globulin administration have been recommended and debated for decades.
Also, such patients might potentially receive Rh immune globulin following an Rh(D)-positive red blood cell exposure.
Additionally, patients with the weak D phenotype are generally not considered candidates for Rh immune globulin administration.
2% of transfusion services indicated that they routinely recommend the administration of Rh immune globulin to patients of childbearing age who are positive for the weak D phenotype and who receive Rh(D)-positive blood components.
9] Thus, the incidence of anti-D alloantibody formation in patients with the weak D phenotype may not be that rare and may partially explain some of the discrepancies noted in this study related to the transfusion of Rh(D)-positive red blood cells and the administration of Rh immune globulin in patients who have the weak D phenotype.
4% of institutions Rh immune globulin is dispensed by the transfusion service rather than by the pharmacy (16.