Rh immune globulin


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Related to Rh immune globulin: Rh incompatibility

Rh immune globulin

Rh immune globulin

RhIg, Rho(D) immune globulin Obstetrics A sterile plasma-based preparation rich in anti-Rh antibodies used to prevent production of Rho(D) antibodies in Rh-negative mothers who may have an Rh-positive infant; its use virtually eliminates HDN due to maternal Rh-antibody production. See Hemolytic disease of the newborn.

Rh immune globulin

A solution of gamma globulin containing anti-Rh; it is given to Rh-negative women at 28 weeks' gestation to minimize the potential for sensitization secondary to transplacental bleeding. The injection is repeated within 72 hr after delivery of an Rh-positive newborn if the mother's indirect and the newborn's direct Coombs tests are negative. The globulin also should be given to Rh-negative women after spontaneous or induced abortion. Previously called Rho(D) immune globulin.
See also: globulin
References in periodicals archive ?
Therefore, most of them will receive a routine, but unnecessary, antenatal injection of Rh immune globulin if pregnant and a second injection of Rh immune globulin postpartum if they deliver an Rh-positive newborn.
Despite the advances in monoclonal antibody technology and RHD genotyping, there are no updated organizational guidelines to advise practitioners whether or not to administer Rh immune globulin to pregnant women with a weak D phenotype.
The findings of the CAP 2012 survey present an opportunity to update guidelines for Rh typing and qualifications for administration of Rh immune globulin to women with a serological weak D phenotype according to specific RHD genotypes.
Policies and procedures related to weak D phenotype testing and Rh immune globulin administration: results from supplemental questions to the Comprehensive Transfusion Medicine Survey of the College of American Pathologists.
Rh immune globulin and the Rhpositive, Du variant, mother.
Supplementary questions related to weak D terms and testing and to the administration of Rh immune globulin in selected clinical situations were included in the 1999 J-A Transfusion Medicine (Comprehensive) and Educational Survey Set of CAP.
Transfusion services were asked if they routinely recommend the administration of Rh immune globulin to those patients found or known to have a weak D phenotype and who receive various Rh(D)-positive blood components.
Percentage of Transfusion Services that Routinely Recommend the Administration of Rh Immune Globulin to Patients With the Weak D Phenotype
For patients who are determined to be Rh(D) negative (ie, not weak D), transfusion services were asked if they routinely recommend the administration of Rh immune globulin to those Rh(D)-negative patients who undergo transfusion with Rh(D)-positive platelets or plasma blood components.