Reye syndrome


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Related to Reye syndrome: aspirin, black mass

Reye syn·drome

(),
an acquired encephalopathy of young children that follows an acute febrile illness, usually influenza or varicella infection; characterized by recurrent vomiting, agitation, and lethargy, which may lead to coma with intracranial hypertension; ammonia and serum transaminase levels are elevated; death may result from edema of the brain and resulting cerebral herniation. May be linked to aspirin ingestion.

Reye syndrome

Neurology A potentially fatal condition characterized by acute encephalopathy and fatty degeneration of liver, with a dose-dependent relationship to use of aspirin in children with viral infections–eg, influenza, varicella-zoster Clinical Vomiting, hepatic dysfunction, variable neurologic impairment–irritable and combative behavior, loss of consciousness, stupor, seizures, coma, death, often preceded by viral URIs or varicella Lab ↑ Transaminases, glutamine and ammonia in CSF, hypoglycemia, metabolic acidosis DiffDx Drug & chemicals–Aspirin, other salicylates, acetaminophen, lead, valproic acid, methyl bromide, hydrocarbons, chlordane, ethanol, disulfiram Infectious–viral encephalitis, hepatitis Metabolic–cystic fibrosis, carnitine deficiency, hereditary fructose intolerance, isovaleric acidemia, urea cycle disorders Others–Pancreatic encephalopathy, acute encephalopathy with fatty metamorphosis of the liver due to cold agglutinin autoimmune hemolytic anemia, toxic encephalopathy Treatment None universally accepted. See Lovejoy's classification, Will Rogers phenomenon.

Reye syn·drome

(rī sin'drōm)
An acquired encephalopathy of young children that follows an acute febrile illness, usually influenza or varicella infection; characterized by recurrent vomiting, agitation, and lethargy, which may lead to coma with intracranial hypertension; ammonia and serum transaminases are elevated; death may result from edema of the brain and resulting cerebral herniation. Strongly associated with aspirin therapy.
Synonym(s): hepatic encephalopathy (2) .

Reye,

Ralph Douglas Kenneth, Australian pediatric pathologist, 1912-1978.
Reye syndrome - an acquired encephalopathy of young children that follows an acute febrile illness, usually influenza or varicella infection.
References in periodicals archive ?
Then, these cells were inoculated with a CSF specimen (100 [micro] L per well) from a patient with a diagnosis of Reye syndrome and cultured at 33[degrees]C for 2 weeks.
Children and teenagers who are receiving long-term aspirin therapy and therefore might be at risk for developing Reye syndrome after influenza season and have a physician prescription for the vaccine.
CDC led the US campaign to immunize all children against vaccine-preventable infectious diseases; efforts to "link" states in search of foodborne disease outbreak causes by using molecular approaches to trace the causative organisms (PulseNet); efforts to translate science to practice, protecting women and children from such emerging infection-related conditions as toxic shock syndrome and aspirin-associated Reye syndrome.
This CD informs the medical profession about the diagnosis and treatment of Reye Syndrome and Reye-like illnesses.
In the next edition, the authors might explore the polymicrobial etiology of Reye syndrome, autoimmune disorders, atherosclerosis, and cancers, such as Kaposi sarcoma, hepatocellular sarcoma, and cervical cancer.
Aspirin medications may increase the risk of Reye syndrome, a rare but serious illness associated with flu and other viral disease, including chickenpox," Tavris said.