Rett syndrome


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Rett syndrome

 [ret]
a pervasive developmental disorder affecting the gray matter of the brain, occurring exclusively in females and present from birth; it is characterized by autistic behavior, ataxia, dementia, seizures, and loss of purposeful use of the hands, with cerebral atrophy, mild hyperammonemia, and decreased levels of biogenic amines.

Rett syn·drome

(ret), [MIM*312750]
1. a pervasive developmental disorder characterized by the development of several specific deficits after an apparently normal prenatal and perinatal period, including deceleration in head growth, loss of purposeful hand skills with deterioration into stereotypical hand movements, impairment in expressive and receptive language, and significant psychomotor retardation;
2. a DSM diagnosis that is established when the specified criteria are met.

Rett syndrome

(rĕt)
n.
An X-linked dominant neurological disorder that occurs almost exclusively in girls, characterized by autism, ataxia, seizures, hypotonia, and purposeless hand movements.

Rett syn·drome

(ret sin'drōm)
A progressive syndrome of autism, dementia, ataxia, and purposeless hand movements; associated with hyperammonemia, principally in girls.

Rett syndrome

A brain disorder affecting only girls and, from the age of 9–36 months, causing progressive loss of recently acquired skills, such as speech and walking, repetitive writhing (athetoid) movements, epileptic seizures, AUTISM and gradual disablement. Brain examination shows a significant reduction in the profusion of the dendritic trees in layers 3 and 5 of the frontal and inferior temporal cortices. The visual cortex remains unaffected. The cause remains obscure but is thought to be the result of a fresh mutation rather than an inherited genetic defect. (First described in 1966 by the Austrian physician Andreas Rett).

Rett,

Andreas, Austrian physician, 1924–.
Rett syndrome - a progressive syndrome of autism, dementia, ataxia, and purposeless hand movements.
References in periodicals archive ?
org is accelerating research for treatments and a cure for Rett syndrome.
She was an inspiration to many other families touched by Rett Syndrome.
The course of Rett Syndrome, including the age of onset and the severity of symptoms, varies from child to child.
Rett Syndrome is a rare neurological and genetic disorder which affects mainly girls.
As news of the death emerged, Rachel Bloom - a founder of Rett Syndrome Research Trust UK - called for more funding to help boost promising research into treatments for the condition.
Rett syndrome is a rare neurodevelopmental disability that is currently considered an autism spectrum disorder (ASD).
Now I am determined to raise awareness of the condition and money for the Rett Syndrome Research Trust UK, which is looking at finding a cure.
I had to do a lot of research into Rett syndrome to make sure I knew exactly what it was before the audition.
The big bike ride organised by Charity Adventure who organise rides throughout the year for different charities, raised about pounds 4,000 to fund research into finding a cure for Rett Syndrome.
She suffered from a rare disorder called Rett Syndrome, and was enjoying her first trip to a children's hospice in Birmingham when she died.
Acorns Children's Hospice and Rett Syndrome Association UK have been chosen by Barclays to benefit from fundraising activites which will take place in branches throughout 2009 which have so far this year raised pounds 30,000.
Background: Rett syndrome is a neurodevelopmental disorder associated with gastroesophageal reflux disease (GERD) and dysphagia.