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Retrovirus |
Also found in: Encyclopedia, Wikipedia, Hutchinson | 0.06 sec. |
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retrovirus /ret·ro·vi·rus/ (ret´ro-vi?rus) a large group of RNA viruses that includes the leukoviruses and lentiviruses; so called because they carry reverse transcriptase.
Retrovirus A family of RNA viruses containing a reverse transcriptase enzyme which allows the viruses' genetic information to become part of the genetic information of the host cell upon replication. retrovirus (ret´rōvīrus), n a virus containing ribonucleic acid rather than deoxyribonucleic acid. retrovirus a member of the family Retroviridae. defective retrovirus a virus unable to replicate independently; commonly the result of loss of part of the envelope gene when leukosis viruses acquire an oncogene. Propagation is achieved by coinfection with a leukosis virus able to provide the envelope for the defective virus. endogenous retrovirus one transmitted in germ-line DNA from an infected parent to offspring. exogenous retrovirus one transmitted horizontally. rapidly transforming retrovirus characterized by rapid oncogenesis attributable to the v-onc gene which they carry. slowly transforming retrovirus weakly oncogencic after a long incubation period. They do not carry the v-onc gene. retrovirus Virology An RNA virus that encodes reverse transcriptase so that its RNA can be transcribed into DNA in a host cell; modified retroviruses are used as vectors to introduce genes–or portions thereof–of interest into eukaryotic cells. See Cloning vector, DNA, Eukaryote, Gene, HIV, HTLV, Reverse transcriptase, RNA, Rous sarcoma virus, Spumavirus, Transciption, Virus. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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