retinoic acid receptor

(redirected from Retinoid receptors)

retinoic acid receptor

nuclear receptor for retinoic acid.

ret·i·no·ic ac·id re·cep·tor

(ret'i-nō'ik as'id rĕ-sep'tŏr)
Nuclear receptor for retinoic acid.
References in periodicals archive ?
To interact with retinoid receptors, retinol must first be metabolized to more active forms, such as retinaldehyde and retinoic acid using several enzymatic steps.
A further indication that the receptor-binding pathway is strongly involved in retinoid dermatitis is the finding that genetically engineered mice born deficient in nuclear retinoid receptors develop neither epidermal hyperplasia nor skin irritation after the application of topical tretinoin.
Retinoid receptors belong to a superfamily of ligand-inducible transcription factors including steroid, vitamin D, thyroid hormone, peroxisome proliferator-activated receptor, and orphan receptors with unknown functions [14].
Adipose tissues have long been recognized as potential sites for RA action, and where retinoid receptors of two different subfamilies (RAR and RXR) are expressed (Haq and Chytil, 1991; Kamei et al.
Preliminary results show that cholecalciferol u pregulares vitamin D and certain retinoid receptors, inhibits growth and invasion, induces differentiation, and decreases the expression of proteins associated with malignant transformation.
1) program and were used to amplify regions of each of the six retinoid receptors and PCR products were visualized on 1.
This subclass of retinoid receptors has biologic activity distinct from that of retinoic acid receptors (RARs).
Researchers have identified several distinct retinoid receptors on cell nuclei membranes that appear related to other receptors known to regulate genes in this way.
The company's retinoid receptors include retinoic acid receptors (RARs), retinoid X receptors (RXRs) and RAR-related orphan receptors (RORs).
Targretin and other RXR modulators modulate immune response by binding to retinoid receptors within cells that play a role in regulating cell differentiation, growth and apoptosis.
Retinoids act by interacting with the cellular retinoid receptors, RAR and RXR, and 9-cis-retinoic acid ('alitretinoin') is believed to be the ligand for RXR, although there is some controversy about this.

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