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Protective effect of erythropoietin on renal ischemia and reperfusion injury.
Expression of GH receptor, IGF-I receptor and IGF-I mRNA in the kidney and liver of rats recovering from unilateral renal ischemia.
Unilateral renal ischemia in rats induces a rapid secretion of inflammatory markers to renal lymph and increased peritubular capillary permeability," The Journal of Physiology, vol.
Notably, postoperative renal function is multifactorial relative to preoperative function, preserved renal mass, and intra-operative renal ischemia.
Mechanism of proximal tubule brush border loss and regeneration following mild renal ischemia.
Researchers at Tulane are utilizing the Zenascope[TM] system to monitor renal ischemia during partial nephrectomy in large animal models, and to monitor physiological changes in tissue in response to investigational therapeutics in cancer and regenerative medicine.
given as a pretreatment, was able to reduce renal ischemia and reperfusion (I/R)-induced injury and oxidant stress.
Page kidney was first defined by Page (6) in 1939 when he wrapped a canine kidney with cellophane and observed the ensuing hypertension, which he proposed to be caused by renal ischemia and hypoperfusion (although others have suggested that the hypertension in this setting may be the result of interstitial nephritis and inflammation due to kidney compression).
However, hematuria in the patient could have been due to severe thrombocytopenia or malaria-induced renal ischemia and acute tubular necrosis.
However, large shunts may lead to renal ischemia, and rupture of large arteriovenous fistulas and pseudoaneurysms can cause hematuria or perigraft hemorrhage.
For now, efforts to prevent acute renal failure should include avoidance or reduction of conditions and agents that increase the risk, including hypotension, nephrotoxins, and renal ischemia.