2009) to amplify the 5' regulatory region
and exon 1 of caprine INHA gene (GenBank No.
Hypermethylation of the gene regulatory regions
is documented for many cancer diseases.
Therefore, the chromatin remodeling complex which was aberrantly formed by AML1-ETO, and the hypermethylation of the CpG islands which were presented in the AML1 binding sites on the EYA4 regulatory region
appeared to be the key regulatory mechanisms for the transcriptional silencing of EYA4 .
In this paper, the 5'-flanking sequence of ChMT was identified, and MRE and octamer-binding site (OBS) element-based promoter truncation analysis was performed in the upstream regulatory region
of the ChMT gene.
Many neuroimaging studies consistently have indicated structural and functional deficits in prefrontal regulatory regions
associated with chronic alcoholism (for review, see Buhler and Mann 2011).
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
The regulatory region
of the human OXTR gene displays binding sites for several transcription factors, such as growth associated binding protein, CCAAT/enhancer-binding protein (C/EBP), activator protein-1 (AP-1), Sp-1, nuclear factor-icB (NK-kB), and NF-interleukin-6 (Kimura et al.
Because deletions in the viral genome have been reported in the VP2 sequence and the regulatory region
of hamster polyomavirus (11), a virus that causes lymphomas, the sequence encompassing part of the VP2 protein and the regulatory region
(4,876-238) of 7 MCPyV isolates were PCR amplified with the primer set RegF/RegR (5'-TGTTCAGCTGTGAACCCAAG-3' and 5'-GAGC CTCTCTTTCTTTCCTATTT-3', respectively), cloned, and sequenced.
The first genetic construct comprises a first regulatory region
operatively linked to a gene of interest and at least one repressor sequence capable of controlling the activity of the first regulatory region
At this stage, equally parsimonious interpretations of the data presented here are that (i) there has been a compaction and simplification of upstream regulatory region
DNA in the sponge lineage, and (ii) a bulk of cis-regulatory DNA is housed elsewhere in the genome.
A 222-bp PCR product is generated from the regulatory region
of the lactase gene and analyzed by melting curve analysis.
The transgenic models we optimized here are based on the fundamental design of composite reporter gene constructs with a hormone-sensitive regulatory region
upstream of a fluorescent protein cDNA.