RNA interference

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Related to Regulatory RNA: regulatory gene

RNA interference

n. Abbr. RNAi
A process in which double-stranded RNA inhibits the expression of genes by triggering degradation of messenger RNAs with complementary sequences.

RNA interference

,

RNAi

The blocking of gene expression by disrupting the translation of messenger RNA into proteins. Synonym: posttranscriptional gene silencing
References in periodicals archive ?
Pollard and her colleagues speculate that this region produces a regulatory RNA and that changes in this RNA contributed to the evolution of the human brain.
By starting and stopping in different places, the transcription machinery can generate a regulatory RNA from a length of DNA that overlaps a protein-coding gene.
With regulatory RNAs appearing to play such an instrumental role in animal development, it's no surprise that scientists are finding disease-associated mutations in regions of the genome formerly regarded as junk.
Scientists at the Ovarian Cancer Institute Laboratory at the Georgia Institute of Technology have found in initial tests that a regulatory RNA called miR-429 may be successful in inducing metastatic or spreading cancer cells to convert back to a less metastatic, non-invasive form.
It was surprising enough to come across a gene that encoded regulatory RNA, and not protein, and then to find that the RNA was so tiny was astonishing," Dr.
As scientists investigate the role of regulatory RNA molecules in the development of disease, they will need to move beyond standard whole tissue expression profiling to a more precise method of identifying the exact cells that are modulated by these molecules.
It may also facilitate delivery of regulatory RNA molecules, including antisense RNA molecules for the management of medically important diseases.

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