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Reed-Sternberg cell

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Reed-Sternberg cell
n.
A giant binucleated or multinucleated acidophilic cell in the tissues in Hodgkin's disease. Also called Sternberg-Reed cell.

Reed-Sternberg cell
Etymology: Dorothy M. Reed, American pathologist, 1874-1964; Karl Sternberg, Austrian pathologist, 1872-1935
one of a number of large, abnormal, multinucleated reticuloendothelial cells in the lymphatic system found in Hodgkin's disease. The number and proportion of Reed-Sternberg cells identified are the basis for the histopathologic classification of Hodgkin's disease.

Reed-Sternberg cell
see Reed-Sternberg cell.


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s lymphoma, is different in that the presence of an abnormal cell called the Reed-Sternberg cell becomes abnormal and copies itself, producing extra cells collectively called a tumor.
Pathologic Diagnosis: Syncytial Variant of Nodular Sclerosing Hodgkin Disease The syncytial variant of nodular sclerosing Hodgkin disease is an unusual form of Hodgkin disease characterized microscopically by the more typical features of nodular sclerosis, as well as the presence of cohesive aggregates of atypical mononuclear Reed-Sternberg cell variants.
A defining attribute of the Reed-Sternberg cell is its expression of the CD30 antigen.
 
 
 
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