Chili Pepper

(redirected from Red Chillies)
Also found in: Dictionary, Thesaurus.

capsicum

(kap-si-kum) ,

Capzasin-HP

(trade name),

Zostrix

(trade name),

capsaicin

(trade name),

chili pepper

(trade name),

African bird pepper

(trade name),

Capsicum annuum

(trade name)

Classification

Therapeutic: analgesics
Oral: Dyspepsia Topical: Arthritis, lower back pain, and neuralgias Intranasal: Headache, perennial rhinitis

Action

Binds to nociceptors in the skin, causing neuronal excitation, heightened sensitivity and cutaneous vasodilation. Initially, a burning or pricking sensation is produced. With repeated use, a period of desensitization occurs caused by substance P depletion.

Therapeutic effects

Decreased pain sensation.

Pharmacokinetics

Absorption: Well absorbed when applied to skin.
Distribution: Unknown.
Metabolism and Excretion: Metabolized by the cytochrome P450 system to active metabolites.
Half-life: 1.6 hrs (topical).

Time/action profile

ROUTEONSETPEAKDURATION
POUnknownUnknownUnknown
TopicalUnknownUnknownUnknown

Contraindications/Precautions

Contraindicated in: Hypersensitivity or allergy; Injured skin or open wounds (topical); Infectious or inflammatory GI conditions (oral); Obstetric: Pregnancy and lactation (oral).
Use Cautiously in: Obstetric: Pregnancy and lactation (topical); Pediatric: Safety and efficacy has not been shown in children; Kidney and/or liver disease (long-term, high doses); Surgery (discontinue use 2 wk prior to procedure).

Adverse Reactions/Side Effects

Dermatologic

  • burning (topical)
  • erythema (topical)
  • urticaria (topical)
  • flushing
  • sweating

Ear, Eye, Nose, Throat

  • cough
  • rhinorrhea
  • lacrimation,

Gastrointestinal

  • GI irritation
  • diarrhea

Hematologic

  • bleeding

Interactions

May ↑ bleeding risk with antiplatelet agents or anticoagulants.May ↑ absorption of theophylline.May ↑ bleeding risk when taken with clove, garlic, ginger, ginseng, and ginkgo.
Oral (Adults) Powder—30–120 mg 3 times daily; Tincture—0.6–2 mL/dose; Oleoresin—0.6–2 mg/dose.
Topical (Adults) Apply cream 3 to 4 times daily (may take up to 14 days to see an effect).
Intranasal (Adults) 0.1 mL of a 10 mM suspension (300mcg/day) applied to nostril.

Availability

Powder:
Capsules:
Tincture:
Topical cream: 0.025% (Zostrix®), 0.075% (Zostrix-HP®), 0.1% (Capzacin-HP®)

Nursing implications

Nursing assessment

  • Assess pain intensity and location before and periodically during therapy.
  • Lab Test Considerations: Monitor: liver and kidney function tests in patients receiving oral therapy. Notes: Capsicum (or cayenne) alters temperature regulation and stimulates circulation.

Potential Nursing Diagnoses

Acute pain (Indications)

Implementation

  • Topical: Apply to affected area not more than 3–4 times daily. Avoid getting medication into eyes or on broken or irritated skin. Do not bandage tightly.
    • Topical lidocaine may be applied during the first 1–2 wk of treatment to reduce initial discomfort.

Patient/Family Teaching

  • Instruct patient on the correct method for application. Rub cream into affected area well so that little or no cream is left on the surface. Gloves should be worn during application or hands should be washed immediately after application. If application is to hands for arthritis, do not wash hands for at least 30 min after application.
  • Advise patient to apply missed doses as soon as possible unless almost time for next dose. Pain relief lasts only as long as capsaicin is used regularly.
  • Inform patient that transient burning may occur with application, especially if applied less than 3–4 times daily. Burning usually disappears after the first few days but may continue for 2–4 wks or longer. Burning is increased by heat, sweating, bathing in warm water, humidity and clothing. Burning usually decreases in frequency and intensity the longer capsaicin is used. Decreasing number of daily doses will not lessen burning but may decrease amount of pain relief and may prolong period of burning.
  • Caution patient to flush area with water if capsaicin gets into eyes and to wash with warm but not hot, soapy water if capsaicin gets on other sensitive areas of the body. A diluted vinegar solution can be used to remove capsicum cream (capsaicin is not water washable).
  • Instruct patients with herpes zoster (shingles) not to apply capsaicin cream until lesions have completely healed.
  • Advise patient to discontinue use and notify health care professional if pain persists longer than 1 mo, worsens, or if signs of infection occur.

Evaluation/Desired Outcomes

  • Decrease in discomfort associated with:.
    • postherpetic neuralgia.
    • disbetic neuropathy.
    • rheumatoid arthritis.
    • osteiarthritis.
  • Pain relief usually begins within 1–2 wks with arthritis, 2–4 wks with nauralgia, and 4–6 wks with neuralgias of the head and neck.
(1) A condiment used in certain cuisines, in particular Mexican, that is particular high in capsaicin
(2) Cayenne, see there, Capsicum frutescens
The intensity of the ‘sting’ of hot chillis is measured in Scoville units
References in periodicals archive ?
We believe in the global vision of Red Chillies to create groundbreaking content out of India," said Netflix founder and CEO Reed Hastings.
Explaining the need for setting up of RCPC in Kunri, he said red chillies were harvested in monsoon season, which becomes the cause of prolonged moisture on the fruit, consequently contaminating the produce with bacteria.
The PMEX Red Chilli Futures Contract has been formulated in such a way that it will provide the processors an opportunity to procure good quality red chillies in a better way.
Chopped Garlic and Chopped Red Chillies are targeting consumers looking to enhance their cooking, and seek ways to make meals easy to prepare.
Bobby Chadha, who is Juhi Chawla's brother, was the CEO of Red Chillies.
Speaking on condition of anonymity, a Red Chillies official said: "They were handling the quotes (money and budgets) so the leak had come from them.
Aflatoxin B1 in 48/183 samples and aflatoxin B2 in 3/183 samples were detected in red chillies imported from India may be due to poor drying and storage conditions as these conditions cause moisture and humidity which are main cause of aflatoxin growth.
To maintain closeness of the story line of the game to the film, it has been actually written by Red Chillies team and Shahrukh, in particular.
Red Chillies Idiot Box, an arm of SRK's Red Chillies Entertainment, which is co-producing the show, stands to gain much of the spoils.
Ingredients 500g ripe tomatoes, halved 2 red chillies, stems removed and deseeded 4 cloves garlic, peeled 2.
500 gms Boneless Chicken; 1 tsp red chilli powder; A' tsp black pepper powder; 1 tbsp ginger -- garlic paste; 2 egg whites; 3 tbsp corn flour; 3 tbsp white flour ( maida ); 2 lemon ( for juice); 3 tbsp yogurt; A- tsp turmeric powder; 3 tbsp Olive oil; 3 red chillies ( dry); 1 tsp mustard seeds; 2 tbsp curry leaves; Salt as required
500g (1lb 2oz) mild red chillies, seeded 250ml (9fl oz) olive or other neutral oil, eg corn