recombinant DNA

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re·com·bi·nant DNA

altered DNA resulting from the insertion into the chain, by chemical, enzymatic, or biologic means, of a sequence (a whole or partial chain of DNA) not originally (biologically) present in that chain.

recombinant DNA

n. Abbr. rDNA
Genetically engineered DNA prepared by transplanting or splicing genes from one species into the cells of a host organism of a different species. Such DNA becomes part of the host's genetic makeup and is replicated.

recombinant DNA

a DNA molecule in which rearrangement of the genes has been experimentally induced. Enzymes are used to break isolated DNA molecules into fragments that are then rearranged in the desired sequence. DNA sequences from another organism of the same or a different species may also be introduced into the molecule, which is then replicated, resulting in both genotypic and phenotypic alterations in the organism that carries the recombinant DNA. See also genetic engineering.

recombinant DNA

DNA produced by the artificial linkage, in the laboratory or factory, of DNA from different sources. See also GENETIC ENGINEERING.

recombinant DNA

  1. DNA produced by joining together DNA sequences from different sources in vitro; often this involves VECTOR (2) DNA and foreign DNA to form a recombinant vector for use in GENETIC ENGINEERING.
  2. DNA produced by natural RECOMBINATION in vivo.

recombinant DNA

DNA transformed by insertion of a sequence of additional/foreign DNA
References in periodicals archive ?
produced by recombinant technology, third-generation B-domain-depleted VIII.
One project in the preclinical stage uses this recombinant technology to develop supportive therapy to restore the immune system after tumour patients have undergone chemotherapy.
Title: Biosimilars in Emerging Economies - Advanced Recombinant Technology Platforms and Low Cost Manufacturing Put India and China at a Strategic Advantage in Biosimilar Production
Department of Health and Human Services (HHS), to fund the development of seasonal and pandemic flu vaccines using recombinant technology.
This technology utilizes LifeSensors' Small Ubiquitin-like MOdifier (SUMO) system and integration of the recombinant technology into an automated robotic platform to screen for novel engineered strains of S.
The recombinant technology used to make Flublok and Panblok is the pandemic solution ; these vaccines can be made safely, accurately and much faster than they could by using other technologies.
Baxter's investigational rVWF concentrate was developed using a plasma- and albumin-free manufacturing method, and represents the largest protein ever produced through recombinant technology.
It has been possible to move quickly and safely to develop the H7N9 vaccine because we use modern, proprietary, recombinant technology that enables us to develop vaccines for potentially deadly viruses without the use of a live disease virus and, therefore, without any risk to personnel.
The application of recombinant technology to plants has led to major advances in plant biology, allowing production of genetically modified plants that are optimized for yield and/or resistant to pathogens/pesticides.
GBI Research, the leading business intelligence provider, has released its latest report, "Biosimilars in Emerging Economies - Advanced Recombinant Technology Platforms and Low Cost Manufacturing Put India and China at a Strategic Advantage in Biosimilar Production" that provides key data, information and analysis of the major trends and issues that affect the emerging biosimilars market.
Earlier this year InNexus announced it developed a novel antibody fragment product, IXSCD11a, directed at treatment of psoriasis and produced by recombinant technology identical to IXS312(VEGF).
If successful in human clinical trials, this advance will usher in the first entirely new way of making therapeutic proteins since the development of recombinant technology more than 30 years ago, with dramatic implications for both patients and industry.

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