receptor-mediated endocytosis


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receptor-mediated endocytosis

the process carried out in CLATHRIN coated pits, whereby specific macromolecules are transported into eukaryotic cells subsequent to binding to specific cell-surface receptors.
References in periodicals archive ?
Renal Uptake of 99mTc-Dimercaptosuccinic Acid Is Dependent on Normal Proximal Tubule Receptor-Mediated Endocytosis.
Moreover, mechanism of nanoparticle mediated drug transport across the BBB appears to be receptor-mediated endocytosis [151].
Moreover, other than neuroprotective compounds monoclonal antibodies are also used to pass through BBB by receptor-mediated endocytosis mechanism.
Many proteins have been shown to be internalized by cells through receptor-mediated endocytosis, a process in which the protein binds to a specific receptor on the cell surface and is subsequently internalized through clatrin-coated pits along the plasma membrane (Goldstein et al.
Clathrin is the major protein component involved in receptor-mediated endocytosis (25).
Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia.
The publication, titled "Characterization of transferrin receptor-mediated endocytosis and cellular iron delivery of recombinant human serum transferrin from rice (Oryza sativa L.
Human kidney is able to reabsorb 95% of all filtered albumin via receptor-mediated endocytosis within proximal tubules (Nielsen 1993).
Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.
Since the initial studies of receptor-mediated endocytosis on LDL (1, 2) and asialoglycoprotein (ASGP) (3, 4), many internalized ligands and their receptors have been identified and characterized (5).
GA is actively transported into human lysosomes via mannose-6-phosphate receptor-mediated endocytosis (5).
Ubiquitin modification of numerous cellular targets is involved in regulating a broad array of cellular processes, among them cell cycle and division, apoptosis, transcription, antigen presentation, signal transduction, receptor-mediated endocytosis, maintenance of the cellular quality control, and modulation of diverse metabolic pathways.

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