Ring Finger Domain

(redirected from Really Interesting New Gene)
Also found in: Acronyms.
A 40-to-60 residue zinc-finger domain macromolecular protein consensus sequence which contains a Cys3HisCys4 amino acid motif that binds two zinc cations, and mediates protein-protein interactions—e.g., with E2 enzyme. They are the specificity determinants for cellular ubiquination and associated with certain transcription factors—e.g., TIF1b, the PML-family, NFX1, XPRF
Types RING-HC, RING-H2
RING is an acronym for Really Interesting New Gene
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