rational drug design


Also found in: Acronyms.

rational drug design

The study of the shape of molecules in order to determine how they will bind receptors on cells or combine with other molecules. Drug design that is based on molecular shape or architecture is an alternative to blindly testing hundreds of molecules to see if one or more of them will bind cellular or molecular targets.
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Rib-X said that its RX-04 programme employs a proprietary approach for rational drug design resulting in entirely new families of compounds that have demonstrated efficacy at low, single doses in murine infection models.
Research chemists involved in rational drug design, and clinicians using knowledge-based therapeutics could be interested.
is a privately held, Canadian biopharmaceutical and chemistry-driven rational drug design company focused on the inhibition of quality enzyme targets associated with disease.
Bearsden is a growing biopharmaceutical company with extensive technology in rational drug design, nucleic acid and medicinal chemistry.
Gleevec(x) is the first cancer treatment to be developed with rational drug design, based on an understanding of how cancer cells work.
Bearsden is a privately held biopharmaceutical company with a broad-based technology in nucleic acid and rational drug design.

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