Based in Dallas, Texas, the Company's lead programs involve paclitaxel (active ingredient in Taxol(R)) production using fermentation and genetic engineering in agreements with Bristol-Myers Squibb, the treatment of polycystic kidney disease using paclitaxel, breast cancer treatment by peptide inhibition of estrogen receptors and Quantum Core Technology(TM), a proprietary rational drug design
He will assist Cytoclonal in the synthesis of drugs from its rational drug design
program through consulting and contract work.
Nasdaq: PCOP), to optimize Cytoclonal's rational drug design
efforts for improving diagnostics and therapeutics for cancer and infectious diseases such as HIV.
Cambridge, MA) using structure-based rational drug design
The Company is a leader in the use of structure- based rational drug design
, an approach to drug discovery that integrates biophysics, biology and medicinal chemistry.
They will then work with Immunex scientists on laboratory activities involving molecular biology, rational drug design
The experience and expertise they bring to TBC will be important assets in the successful integration of IPI's rational drug design
technology with TBC's therapeutics program for treating cardiovascular and inflammatory diseases.
In February, DOR announced that it had initiated a rational drug design
program to identify oral, small molecule drugs to counter the deadly effects of botulinum toxin exposure through a collaboration with Blue Dolphin, LLC, a firm specializing in rational drug design
IPI), a rational drug design
company focused on developing small molecule therapeutics.
In 2003 the Company introduced the TOPAZ(R) system, which speeds the discovery of protein structure, an essential step in rational drug design
The patent, titled "A Method of Rational Drug Design
of Compounds that Mimic Conformational Features of Selected Peptides," covers a supercomputer-based method that is proprietary to IPI.