RAST

RAST radioallergosorbent test.

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RAST

abbr.

radioallergosorbent test

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RAST.

See radioallergosorbent test.

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radioallergosorbent test (RAST) [ra″de-o-al″er-go-sor´bent]

a radioimmunoassay for the measurement of extremely small amounts of specific IgE antibody to a variety of allergens in the serum of a patient, using an allergen complex fixed in a solid-phase matrix, passing the serum over the matrix so the allergen can catch and bind specific IgE antibodies, and detecting the antibody using radiolabeled anti–human IgE antibody. Uptake of the labeled antibody is proportional to the level of specific serum IgE antibodies to the allergen. RAST is used as an alternative to skin tests to determine sensitivity to suspected allergens.

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RAST,

n.pr See test, modified radioallergosorbent.

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RAST

radioallergosorbent test.

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RAST

Radioallergosorbent test Immunology A 'solid phase' radioisotopic method for quantifying specific allergenic IgE antibodies in serum, which is similar to an agglutination test. See Mail-order medicine, Patch testing.