rabbit hemorrhagic disease

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rabbit hemorrhagic disease

a highly fatal, contagious disease of European rabbits (Oryctolagus cuniculus) but other rabbit species and other wildlife are not susceptible. Caused by rabbit hemorrhagic disease virus (genus Lagovirus, family Caliciviridae); the virus while typical of caliciviruses has not been cultivated. The disease is related to European Brown Hare syndrome but cross-transmission between hares and rabbits of either virus does not occur; spread is by contact, possibly by infected feces, fomites, possibly by spread of carrion by birds, and by recently contaminated insects such as bush flies. After infection rabbits show few clinical signs other than depression and immobility and die after an illness of about 18 hours. Characteristic gross necropsy lesions are enlargement of the liver and spleen and small, focal, pulmonary hemorrhages. There is massive liver necrosis which is believed to be the trigger for disseminated intravascular coagulation. Rabbits less than 6 weeks of age are curiously not susceptible to fatal disease. An effective vaccine is available. Called also rabbit calicivirus disease.
References in periodicals archive ?
Pathogenic, antigenic, and molecular properties of rabbit haemorrhagic disease virus (RHDV) isolated from vaccinated rabbits: detection and characterization of antigenic variants.
Emergence of a new lagovirus related to rabbit haemorrhagic disease virus.
Detection of the new emerging rabbit haemorrhagic disease type 2 virus (RHDV2) in Sicily from rabbit (Oryctolagus cuniculus) and Italian hare (Lepus corsicanus).
Rabbit haemorrhagic disease, Australia--immediate notification report.
Presence of rabbit haemorrhagic disease virus antigen in rabbit tissues as revealed by a monoclonal antibody dependent capture ELISA.
Increased virulence of rabbit haemorrhagic disease virus associated with genetic resistance in wild Australian rabbits (Oryctolagus cuniculus).
An in vivo system for directed experimental evolution of rabbit haemorrhagic disease virus.
Observations on the impacts of rabbit haemorrhagic disease on agricultural production values in Australia.
Now known as rabbit haemorrhagic disease (RHD), the affliction spread quickly.
Steve Davidson reports on whether the land is bouncing Back in the wake of rabbit haemorrhagic disease.