PDE6B

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PDE6B

A gene on chromosome 5q31.2-q34 that encodes the beta subunit of a herterotrimeric (one alpha, one beta and two gamma subunits) cyclic nucleotide phosphodiesterase, which hydrolyses cGMP to 5'-GMP. Expressed in retinal rods, PDE6B is a key phototransduction enzyme in transmitting and amplifying visual signals.

Molecular pathology
PDE6B mutations are linked to retinitis pigmentosa and autosomal dominant congenital stationary night blindness.
References in periodicals archive ?
We successfully sequenced, with both direct sequencing and 454 pyrosequencing, five nuclear introns for the 2551-51657 sample that showed some variation that might be evidence of 'Apapane and 'I'iwi specific alleles (GAPD and RP40, [Reding et al.
G Feather 2551-51657 (454, %): 100%A 100%C 100%T 100%G Feather 2551-51657 (coverage): 46x 46x 52x 36x Supports hybrid status N N N N RP40 'Apapane: G C c G/A 'I'iwi: G T A A Feather 2551-51657 (Sanger): -- C/T C/A G/A Feather 2551-51657 (454, %): 71%G 56%T 53%A 56%A Feather 2551-51657 (coverage): 7x 66x 118x 115x Supports hybrid status Y Y Y ?
T55, T56 RP39 Jeffrey and Gu to T57, T58 RP40 Ramanathan et.
wt%] Resin 100 0 RP05 95 5 RP10 90 10 RP15 85 15 RP20 80 20 RP30 70 30 RP40 60 40 RP60 40 60 Rec.
HID Global of Irvine, California, has launched a new version of its versatile RP40 multiCLASS reader.
HID Corporation of Irvine, California, has introduced the RP40 multiCLASS reader, which combines the company's Prox 125 kHz proximity and iCLASS 13.
HID Global, a leading manufacturer in the access control industry, today announced that its iCLASS[R] R10, R30, R40, RK40 and RP40 model access control readers have been approved by U.
HID Corporation, the premier manufacturer of contactless access control cards and readers for the security industry, today announced the company's newest access control reader, named RP40 multiCLASS(TM), that combines its Prox 125 kHz proximity and iCLASS(R) 13.