polymerase

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Related to RNA-dependent RNA polymerase: replicase

polymerase

 [pah-lim´er-ās]
an enzyme that catalyzes polymerization.
polymerase chain reaction a rapid technique for in vitro amplification of specific DNA or RNA sequences, allowing small quantities of short sequences to be analyzed without cloning.

pol·ym·er·ase

(pol-im'ĕr-ās),
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

/po·lym·er·ase/ (pah-lim´er-ās) an enzyme that catalyzes polymerization.

polymerase

(pə-lĭm′ə-rās′, -rāz′, pŏl′ə-mə-)
n.
Any of various enzymes, such as DNA polymerase, RNA polymerase, or reverse transcriptase, that catalyze the formation of polynucleotides of DNA or RNA using an existing strand of DNA or RNA as a template.

polymerase

[pə·lim′ər·ās]
any enzyme that catalyzes polymerization, especially of nucleotides to polynucleotides.

POLA1

A gene on chromosome Xp22.1-p21.3 that encodes the catalytic subunit of DNA polymerase that plays a key role in initiating DNA replication.

pol·ym·er·ase

(pŏ-lim'ĕr-ās)
General term for any enzyme catalyzing a polymerization, as of nucleotides to polynucleotides, thus belonging to EC class 2, the transferases.

polymerase

Any enzyme that promotes the linkage of a number of similar or identical chemical subunits into repetitive long-chain molecules (polymers), especially of NUCLEOTIDES to form DNA or RNA. Derivation as in POLYMER with the -ase suffix denoting an enzyme.

polymerase

an enzyme that catalyses the joining of DNA or RNA nucleotides.

polymerase

an enzyme that catalyzes polymerization, particularly of nucleic acids.

polymerase chain reaction
see pcr1.
RNA polymerase
1. an enzyme that synthesizes an RNA copy of the sequence in a limited region of DNA in a process known as DNA transcription. Called also DNA-dependent RNA polymerase.
2. a viral enzyme that synthesizes RNA from an RNA template during viral replication. Called also RNA-dependent RNA polymerase.
RNA-dependent RNA polymerase
see RNA polymerase (above).
Taq polymerase
a DNA polymerase that functions at high temperature; derived from the bacterium Thermus aquaticus and used in the polymerase chain reaction.
References in periodicals archive ?
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site.
Inhibitex is developing a series of proprietary nucleotide inhibitors that target the RNA-dependent RNA polymerase (NS5b) of HCV.
We also constructed a phylogenetic tree by the neighbor-joining method using RNA-dependent RNA polymerase gene nucleic acid sequences to compare the isolate we obtained to representative SFTSV strains from China and Japan; the isolate and the other strains were closely related (95.
Genelabs' HCV drug discovery program is focused on inhibition of hepatitis C virus replication by selectively targeting an HCV-specific enzyme known as the RNA-dependent RNA polymerase.
Andres Tellez, principal, business development and strategy, served as the lead author on a research article published in The Journal of Molecular Biology, entitled "Interstitial contacts in an RNA-dependent RNA polymerase lattice.
Screening for CoVs was done by nested reverse transcription PCR using broadly reactive oligonucleotide primers targeting a conserved region in the RNA-dependent RNA polymerase (RdRp) gene (online Technical Appendix).