RNA polymerase


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Related to RNA polymerase: RNA polymerase II

nu·cle·o·tid·yl·trans·fer·as·es

(nū'klē-ō-tī'dĭl-trans'fĕr-ās'ĕz),
Enzymes that catalyze the transfer of transferring nucleotide residues (nucleotidyls) from nucleoside di- or triphosphates into dimer or polymer forms. Some nucleotidyltransferases bear specific names (for example, adenylyltransferases), trivial names indicating the linkage hydrolyzed in the synthesis (pyrophosphorylases, phosphorylases), or names indicating the material that is synthesized (for example, RNA or DNA polymerase).

RNA polymerase

n.
A polymerase that catalyzes the synthesis of a complementary strand of RNA from a DNA template, or, in some viruses, from an RNA template.

RNA polymerase

an enzyme that catalyzes the assembly of ribonucleoside triphosphates into RNA, with single-stranded DNA serving as the template. Also called RNA nucleotidyltransferase.

RNA polymerase

An enzyme that catalyses the joining of appropriate NUCLEOTIDES to form a molecule of RNA, using DNA as a template.

RNA polymerase

one of several enzymes that catalyses the formation of RNA molecules from DNA templates during TRANSCRIPTION. see OPERON MODEL.

polymerase

an enzyme that catalyzes polymerization, particularly of nucleic acids.

polymerase chain reaction
see pcr1.
RNA polymerase
1. an enzyme that synthesizes an RNA copy of the sequence in a limited region of DNA in a process known as DNA transcription. Called also DNA-dependent RNA polymerase.
2. a viral enzyme that synthesizes RNA from an RNA template during viral replication. Called also RNA-dependent RNA polymerase.
RNA-dependent RNA polymerase
see RNA polymerase (above).
Taq polymerase
a DNA polymerase that functions at high temperature; derived from the bacterium Thermus aquaticus and used in the polymerase chain reaction.
References in periodicals archive ?
Rapid kinetic analysis of transcription elongation by Escherichia coli RNA polymerase.
Koleske have evidence that, in yeast, several SRB proteins chair a committee - called a holoenzyme - that includes RNA polymerase and several other substances important for reading the genetic code.
BCX5191 inhibits the viral RNA polymerase enzyme across genotypes 1-4 at sub-micromolar concentrations (0.
RNA polymerase [beta]-subunit-based phylogeny of Ehrlichia spp.
The Kirkegaard Lab at Stanford and the Bullitt Lab at Boston University initially discovered the RNA polymerase lattices and established the scientific foundations that enabled Dr.
Briefly, RNA was transcribed in vitro by T7 RNA polymerase (RiboMax RNA production system, Promega, Madison, WI, USA) from plasmids containing the respective PCR target region, and plasmid DNA was digested with DNase.
PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an enzyme that is necessary for hepatitis C viral replication.
svRNAs were found to mediate their activity by direct association with the viral RNA polymerase enzyme, representing a distinct mechanism of action as compared with other classes on small non-coding RNAs, such as microRNAs, which act by controlling gene expression through interactions with target mRNAs.
These characteristics have been acquired mainly through mutations in the RNA polymerase (PB2) gene, insertions in the HA gene, and deletions in the NA and nonstructural (NS) genes.
Inhibitex is developing a series of proprietary phosphoramidates, or protide nucleoside inhibitors, that target the RNA-dependent RNA polymerase (NS5b) of HCV.
Director of Medicinal Chemistry at Genelabs, entitled "GL59728: A Potent Allosteric Inhibitor of the HCV NS5b RNA Dependent RNA Polymerase with Excellent Pharmacokinetic Properties.
The first ORF (ORF1) encodes a polypeptide with regions of similarity to helicase, cysteine proteinase, and RNA-dependent RNA polymerase (RdRp)-encoding regions of picornaviruses (5).