PRDM2

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PRDM2

A gene on chromosome 1p36.21 that encodes a tumour suppressor zinc finger protein of the nuclear histone/protein methyltransferase superfamily, which binds to the retinoblastoma protein, oestrogen receptor and the TPA-responsive element (MTE) of the haeme-oxygenase-1 gene. PRDM2 may:
• Play a role in regulating transcription during neuronal differentiation;
• Activate transcription of the haeme-oxygenase-1 gene;
• Be a specific effector of oestrogen activty.

Molecular pathology
PRDM2 activation may be linked to retinoblastoma.
References in periodicals archive ?
The Dot Hill AssuredSAN platform provides a scalable foundation for the virtual server architecture at RIZ IT-Motion.
Doctors, architect firms and other consultation-based services feature regularly in our customer base," explained Calin Rotaru, co-founding partner at RIZ IT-Motion.
Forward-looking statements include statements regarding: the size and timing of orders placed by RIZ IT-Motion or Stordis; any improvement to Dot Hill's financial results due to its relationship with RIZ IT-Motion or Stordis and; the benefits and performance of Dot Hill's products in any particular environment.
Martin Hell, CTO of RIZ, said, "We are pleased to be working closely together with a leading technology firm such as Accellion, to enhance and leverage our current infrastructure and market position to offer new online storage services to our customers in Central and Eastern Europe.
Our joint company will offer the unparalleled security, reliability, resilience and redundancy, which RIZ has already established for its banking and insurance customers, to other businesses across Europe.