TAP1

(redirected from RING4)

TAP1

A gene on chromosome 6p21.3 that encodes a member of the MDR/TAP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which plays a role in multidrug resistance. TAP1 pumps degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment.

Molecular pathology
TAP1 mutations have been tentatively linked to ankylosing spondylitis, type 1 diabetes and coeliac disease.
References in periodicals archive ?
RING4 properties are those properties with zip codes outside Highway 1604 but within the boundaries of Bexar County.
The three rings (RING1, RING2, and RING3) are relative to the omitted RING4 (the outer ring).