RFLP


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RFLP

restriction fragment length polymorphism (RFLP)

a difference in the DNA sequences of homologous chromosomes as revealed by different lengths of the restriction fragments produced by enzymatic digestion of a selected region of chromosomes. RFLPs are believed to be inherited according to mendelian laws and have been used to locate the genes associated with several inherited disorders, including Huntington's disease.

RFLP

Restriction fragment length polymorphism Molecular medicine A local variation in the DNA sequence of an individual which may be detected by restriction endonucleases–which 'cut' the double-stranded DNA whenever they recognize a certain highly-specific oligonucleotide sequence or 'restriction' site. See DNA, DNA sequence, Linkage map, Marker, Mutation, Physical map, Polymorphism.

RFLP

Abbreviation for restriction fragment length polymorphism.

RFLP

abbrev. RESTRICTION FRAGMENT LENGTH POLYMORPHISM.

RFLP

restriction fragment length polymorphism.
References in periodicals archive ?
Following an explanation of the RFLP method, the students were divided into approximately three groups in order to perform duplicate gel electrophoresis on the patient samples.
8) 30 BCC + 9 from other specimens Year of isolation (PGIMER) Genomospecies RFLP & source 2002 (identified by API 20 NE) 2004 (Nov, 2004-Jan 2005) 2005 1 - B.
One obvious advantage associated with the use of RFLP markers is the ability to distinguish between homozygous and heterozygous resistant plants.
Our studies indicate that RFLP analysis using general fungal primers are not likely to be useful in identifying species or reconstructing phylogenetic relationships.
RFLP analysis of Centropristis PCR products was simulated with the RFLP analysis tool in the Vector NTI program (Informax Inc.
The linkage map was created using the segregating loci detected by SSR and RFLP markers.
1), possibly because of informative polymorphic sites that were not detected by RFLP analysis.
While RFLP requires bigger samples of DNA, PCR applications require minute amounts, sheriff's senior criminalist Steve R.
improvements in RFLP typing have allowed the FBI to examine six loci in less than 2 weeks, a process that once took more than three times that long and involved only four sites.
The CATIA Systems portfolio now includes interoperability with leading system controller vendors, such as Simulink, as well as full RFLP definition and traceability within CATIA.