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RFLP |
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restriction fragment length polymorphism (RFLP), a difference in the DNA sequences of homologous chromosomes as revealed by different lengths of the restriction fragments produced by enzymatic digestion of a selected region of chromosomes. RFLPs are believed to be inherited according to mendelian laws and have been used to locate the genes associated with several inherited disorders, including Huntington's disease. RFLP restriction fragment length polymorphism. RFLP Restriction fragment length polymorphism Molecular medicine A local variation in the DNA sequence of an individual which may be detected by restriction endonucleases–which 'cut' the double-stranded DNA whenever they
recognize a certain highly-specific oligonucleotide sequence or 'restriction' site. See DNA, DNA sequence, Linkage map, Marker, Mutation, Physical map, Polymorphism. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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