PDE6B

(redirected from RD1)
Also found in: Acronyms.

PDE6B

A gene on chromosome 5q31.2-q34 that encodes the beta subunit of a herterotrimeric (one alpha, one beta and two gamma subunits) cyclic nucleotide phosphodiesterase, which hydrolyses cGMP to 5'-GMP. Expressed in retinal rods, PDE6B is a key phototransduction enzyme in transmitting and amplifying visual signals.

Molecular pathology
PDE6B mutations are linked to retinitis pigmentosa and autosomal dominant congenital stationary night blindness.
References in periodicals archive ?
The RD1 is self-priming and is able to tolerate suspended solids and run dry without damage.
Real Interest Rates French and Poterba McCauley and Zimmer Weights Weights Equity Assumptions RD1 RD2 RD3 RD1 RD2 RD3 Average RE1 2.
Genomic interrogation of the dassie bacillus reveals it as a unique RD1 mutant within the Mycobacterium tuberculosis complex.
By January 1998, the group had homed in on RD1 and confirmed that it has a redshift of 5.
REMAINING FIXTURES: RD1 - Lower Maze v Seapatrick; Oxford United v Banbridge AFC; Camlough Rovers v Markethill Swifts; Crewe United v Portadown BBOB; RD2 Broomhedge v Seagoe United.
RD and SNP typing showed a consistent pattern among the isolates, with presence of regions RD1, RD2, RD4, RD5a (Rv2348), RD6, and RD13-RD16 and absence of regions RD3, RD5b (plcA), and RD7-RD12 (online Technical Appendix Table 1).
These authors found RD1 genes in NTMs that were causing human disease, including M.
das] is deleted and 318 bp when RD1 is intact) but still had no amplification.
Tenders are invited for Bed concrete & toe wall from RD1.
For subspecies identification, a conventional PCR protocol employing primers flanking the RD1 region of F.