renin-angiotensin system

(redirected from RAS system)
Also found in: Encyclopedia.

re·nin-an·gi·o·ten·sin sys·tem

a selective regulator of the aldosterone biosynthetic pathway that acts by increasing aldosterone production and sodium retention as a result of volume depletion, with resulting increased renin production in the kidney and conversion of angiotensin I in the plasma to angiotensin II.

renin-angiotensin system

the regulation of sodium balance, fluid volume, and blood pressure. In response to reduced perfusion, renin is secreted, which hydrolyzes a plasma globulin to release angiotensin I, which is rapidly hydrolyzed to angiotensin II, a powerful vasoconstrictor; angiotension II also stimulates aldosterone secretion, which causes sodium retention, an increase in blood pressure, and restoration of renal perfusion, which shuts off the signal for renin release (negative feedback). Angiotensin-converting enzyme also deactivates bradykinin, a vasodilator. Also called renin-angiotensin-aldosterone system.
enlarge picture
Renin-angiotensin system

re·nin-an·gi·o·ten·sin sys·tem

(RAS) (rē'nin-an-jē-ō-tensin sistĕm)
Selective regulator of the aldosterone biosynthetic pathway that acts by increasing aldosterone production and sodium retention due to volume depletion.

renin

a proteolytic enzyme synthesized, stored and secreted by the juxtaglomerular cells of the kidney; it plays a role in regulation of blood pressure by catalyzing the conversion of the plasma glycoprotein angiotensinogen to angiotensin I. This, in turn, is converted to angiotensin II by an enzyme that is present in relatively high concentrations in the lung. Angiotensin II is one of the most potent vasoconstrictors known, and also is a powerful stimulus of aldosterone secretion.

renin-angiotensin system
renin, secreted by the juxtaglomerular apparatus, activates the precursor angiotensinogen. This liberates angiotensin I, then angiotensin II, a vasoconstrictor and stimulant to the secretion of aldosterone.
big renin
a relatively inactive protein with a higher molecular weight than normal renin, which is activated after exposure to low pH or to proteolytic enzymes.
References in periodicals archive ?
Similarly the RAS system is also split and operated as two separate systems.
Over the last 20 years a paradigm shift concerning the RAS system has occurred.
The RAS system uses powerful and advanced tools, which enables intricate, precise surgery to be carried out in patients.
MaxStat can help IT professionals at both ISP's and corporations determine what sort of use their RAS system undergoes.
Tenders are invited for Construction Of Platform Drainage System And Roof For Putting The Ras System Under Nfdb Indicus Project At Muttukadu Experimental Station Of Ciba At Muttukadu Chennai
By leveraging standard print stream technology to pull data into the RAS system where the real magic begins.
The RAS system is characterized by a network of regional joint ventures that will facilitate manufacturing, assembly and sales activities in specific geographic market areas throughout the U.
Chapters contained in this book include: Chapter 1: Introduction to withholding tax Chapter 2: An overview of withholding tax regimes Chapter 3: Contractual tax Chapter 4: Technology Chapter 5: Basic reclaims systems Chapter 6: Relief at source and treaty benefit systems Chapter 7: The US advanced RAS system Chapter 8: The Japanese system Chapter 9: The system in the Irish Republic Chapter 10: The future of withholding tax regimes Chapter 11: SWIFT messaging Chapter 12: Benchmarking
For the present time, a 5th pump that would be used as an on the-shelf stand-by unit would provide the additional redundancy and flexibility to the RAS system is strongly recommended.
GLMC was able to successfully mine accounts receivable information (AR) from an old AS400 directly to the RAS system prior to cutting over to a new AS400 system.
By leveraging standard print stream technology to pull the data and then once in their RAS system, the magic begins.
To the risk of failure to keep the conversion effort and training costs minimal, the new server system 100% must be compatible with the existing infrastructure (especially in the Parallel Sysplex with IBM z196, EMC DCX4-S SAN Directors, Cisco Catalysts 6500, RAS system of the company , etc.