RANTES


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Related to RANTES: Mcp-1, Eotaxin, IP-10

RANTES

Acronymic construction for a member of the interleukin-8 superfamily of chemokines. This cytokine is an 8-kD protein that is a selective chemoattractant for memory T lymphocytes and monocytes.
[Regulated on activation, normal T expressed and secreted]

RANTES

Regulated upon Activation, Normally T-expressed, and presumably Secreted. A widely used popular name for what is officially known (per HUGO nomenclature) as CCL5, see there.
References in periodicals archive ?
3, cotreatment of TNF-[alpha] and INF-[gamma] significantly increased levels of chemokines MDC, TARC, RANTES, and IL-8 in HaCaT cells.
The clear association between survival and increased RANTES in pediatric patients also suggests that a better understanding of the mechanisms and molecular consequences of increased levels of this chemokine could be useful in future therapeutic design, especially in design of drugs that induce a stronger, earlier, antigen-specific T cell response.
Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury.
From there, they dissected the desired section of the RANTES protein and worked to stabilize it without compromising its protective effects.
8) A thymus- and activation-regulated chemokine (TARC) is involved in the recruitment of Th2 cells, as is RANTES, and a recent study has found increased levels of TARC and IL-5 in BAL from CEP patients, but not in patients with other interstitial lung diseases.
RANTES normally binds to one of several cell-surface proteins, known as chemokine receptors.
This also occurred with RANTES, a C-C chemokine with chemoattractant activity for eosinophils, monocytes, and T lymphocytes.
4% at dilutions required for measuring IL-1[beta], IL-6, MCP-1, and RANTES, and 0.
Enzyme-linked immunosorbent assays (ELISAs) for MMP-1, RANTES (regulated on activation, normal T-expressed and secreted), and IP-10 (interferon-[gamma]-induced protein 10 kDa, CXCL10) were conducted using commercially available kits.
CCR5 plays a role in mediating leukocyte chemotaxis in response to its ligands, which include RANTES, MIP-1a, and MIP-1b.
p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells.