RAB21

(redirected from RAB21, member RAS oncogene family)

RAB21

A gene on chromosome 12q21.1 that encodes a member of the Rab subfamily of Ras-related small GTPases. RAB21 regulates integrin internalisation and recycling, cell adhesion and migration. During mitosis of adherent cells, RAB21 controls the endosomal trafficking of integrins as required for cytokinesis.