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quinupristin

   Also found in: Wikipedia 0.01 sec.
quinupristin /quin·u·pris·tin/ (kwin-u´pris-tin) a semisynthetic antibacterial used in conjunction with dalfopristin against various gram-positive organisms, including vancomycin-resistant Enterococcus faecium.
quinupristin
[kwinu′pris-tin]
a semisynthetic antibacterial effective against a variety of gram-positive organisms. It is used in conjunction with dalfopristin in the treatment of serious bacteremia caused by vancomycin-resistant Enterococcus faecium and complicated skin and skin structure infections caused by Streptococcus pyogenes or methicillin-sensitive Staphylococcus aureus. It is administered intravenously.

quinupristin [kwin-u´pris-tin]
a semisynthetic antibacterial effective against a variety of gram-positive organisms. It is used in conjunction with dalfopristin in the treatment of serious bacteremia caused by vancomycin-resistant Enterococcus faecium and complicated skin and skin structure infections caused by Streptococcus pyogenes or methicillin-sensitive Staphylococcus aureus; administered intravenously.

quinupristin
See Synercid®.


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Based on the Naranjo probability scale, the likelihood that quinupristin dalfopristin caused the anemia and reticulocytopenia is probable.
New antibiotics to use against VRE have been developed such as linezolid, quinupristin, tigecycline, daptomycin, and oritavancin.
Although, as a streptogramin B, quinupristin is cross-resistant with macrolides and lincosamides, dalfopristin is a streptogramin A and not part of this resistance pattern.
 
 
 
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