quinidine /quin·i·dine/ (kwin´ĭ-dēn) the dextrorotatory isomer of quinine, used in the form of the gluconate, polygalacturonate, and sulfate salts in the treatment of cardiac arrhythmias; also used in the treatment of severe falciparum malaria.
quinidine
quinidine
quin·i·dine (kw n -d n )n. A colorless crystalline alkaloid that is a stereoisomer of quinine and is used as a treatment for malaria and cardiac arrhythmias. |
quinidine
[kwin′ədēn, -din]
an antiarrhythmic agent administered as a bisulfate, gluconate, or polygalacturonate or as sulfate salts.
indications It is prescribed in the treatment of atrial flutter, atrial fibrillation, premature ventricular contractions, and tachycardias.
contraindications Known hypersensitivity to this drug prohibits its use. It is contraindicated in thrombocytopenia, myasthenia gravis, and some arrhythmias, particularly those associated with heart block.
adverse effects Among the most serious adverse effects are cardiac arrhythmia, hypertension, and cinchonism. Rare but potentially fatal hypersensitivity reactions such as anaphylaxis and thrombocytopenia may occur. Diarrhea, nausea, and vomiting are common.
quinidine
the dextrorotatory isomer of quinine, used in treatment of cardiac arrhythmias. Several salts are used, including the gluconate, sulfate and bisulfate.
quinidine
Duraquin®, Quinaglute® Cardiology A class Ia antiarhythmic that ↓ myocardial excitability, conduction velocity, and contractility. See Therapeutic drug monitoring.
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