Signs of bilateral basal pneumonia developed, and
Q-fever serologic tests were positive: total antibody titers to phase-II antigen by IF [is greater than or equal to] 1:1280 (threshold [is greater than or equal to] 1:80), and IgM titer [is greater than or equal to] 1:320 (threshold [is greater than or equal to] 1:20).
These changes also influenced the occurrence and seasonality of human Q-fever Bulgaria.
The largest Q-fever outbreak was registered in Panagyurische (central part of [ILLEGIBLE TEXT] Bulgaria) in the 1990s, after an influenza epidemic (end of 1992, beginning of 19 January to June 1993, a second epidemic wave with more than 2,000 cases of an flulike respiratory illness and bronchopneumonia occurred.
A Q-fever outbreak occurred in Panagyurische again in April to June 1995 as [ILLEGIBLE TEXT] serologically in 78% of 89 patients admitted to the local hospital with [ILLEGIBLE TEXT] Acute Q fever was diagnosed in 28 (31%) on the basis of seroconversion or [ILLEGIBLE TEXT] antibody titers.
Acute Q-fever diagnosis was based on seroconversion or fourf antibody titers.
Chronic Q-fever cases manifesting as endocarditis were confirmed serologically titers from 640 to 1 mi of phase I- and phase II- C.
burnetii by MA were found in 16 of 18 aborting [ILLEGIBLE TEXT] titers of 10 to 320, which indicates the possibility of acute Q-fever infection [ILLEGIBLE TEXT] pregnancy.
This explanation is supported by results of a serologic survey (carrie 1989 to 1996) for Q-fever antibodies in groups of farmers or in patients with [ILLEGIBLE TEXT] burnetii infection.
The use of CF, which is sensitive to Q-fever antibodies than other serologic tests (e.
Similarly, observation patients from other Q-fever epidemics (including those with 98 cases in a cotton-plant in nearby Southern Moravia in 1980 [29]) was also negative.
Lessons Learned from Q-Fever Outbreaks in Bulgaria and [ILLEGIBLE TEXT]
Sensitivity of serologic tests for screening Q-fever antibodies increased [ILLEGIBLE TEXT] MA and from MIF to ELISA (27).
