praziquantel

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praziquantel

 [pra″zĭ-kwon´tel]
a broad-spectrum anthelmintic used for treatment of a wide variety of parasitic fluke and tapeworm infections; administered orally.

praziquantel

/pra·zi·quan·tel/ (pra″zĭ-kwahn´t'l) a broad-spectrum anthelmintic used for the treatment of a wide variety of fluke and tapeworm infections.

praziquantel

(prā′zə-kwŏn′tl)
n.
A drug, C19H24N2O2, that kills trematodes and tapeworms parasitic to humans, used especially in the treatment of schistosomiasis.

praziquantel

Biltracide® The antiparasitic of choice for schistosomiasis–S haematobium, S japonicum; flukes or Trematoda–eg, Clonorchis sinensis, Opisthorchis viverrini, Paragonimus buski, Heterophyes heterophyes, Metagonimus yokogawai; tapeworms–Hymenolepsis nana, Taenia solium Side effects Drowsiness, headache, nausea, backache, abdominal discomfort

praziquantel

An ANTHELMINTIC drug used to dispose of tapeworms. The drug is on the WHO official list. A brand name is Cysticide.

praziquantel

a widely used cestocide in dogs and cats. Has a very high efficiency against Echinococcus granulosus, removing all of the worms with a single dose. Called also Droncit.
References in periodicals archive ?
The development of new schistosomicidal drugs and the identification of new schistosomicidal molecules have been highly encouraged, mainly because the treatment of schistosomiasis relies on a single drug, PZQ (Gaba et al.
PZQ (5 [micro]M) caused 100% mortality, whereas no effect was observed in worms in the negative (RPMI 1640 medium) and control (RPMI medium plus 0.
mansoni ATP diphosphohydrolase inhibitors could be also active against juvenile schistosomes, unlike PZQ, which is inactive.
Abbreviations: PZQ, praziquantel; PaI, crude dichloromethane extract from inflorescences of P.
The PZQ dose used, in 45-day-infected mice, showed high percentage in reducing the overall rate of worm burden (94.
However, during the adult worms stage, compared to control, [beta]-lap and PZQ significantly reduced the percentage of immature eggs in 20% and reaching zero percent, respectively.
When animals were treated with PZQ or [beta]-lap, 45 days after infection, the exudative granulomatous reaction showed less eosinophilic infiltration, granuloma circumscription and eggs degeneration more evidently than in untreated infected controls (Fig.
0001) in the average number of hepatic granulomas in all the groups treated with [beta]-lap or PZQ (Table 1).
The group treated with PZQ presented a slight reduction in the granuloma diameter, but not a significant one (Fig.
In addition, the ovicidal action of PZQ caused inviability of eggs by retraction of miracidia, mostly of mature eggs.