pyruvate dehydrogenase complex(redirected from Pyruvate translocase)
a structurally distinct collection of enzymes containing pyruvate dehydrogenase (lipoamide), dihydrolipoyl transacetylase, and dihydrolipoyl dehydrogenase.
pyruvate dehydrogenase complex
a multienzyme complex consisting of at least three distinct enzymes that catalyzes the formation of acetyl coenzyme A from pyruvate and coenzyme A. The acetyl coenzyme A is used in fatty acid synthesis, for acetylations, and for oxidation by means of the citric acid cycle. Deficiency of any component of the complex results in excess of lactic acid in the blood, ataxia, and psychomotor retardation.