methylglyoxal

(redirected from Pyruvaldehyde)

meth·yl·gly·ox·al

(meth'il-glī-ok'săl),
Pyruvaldehyde; the aldehyde of pyruvic acid; an intermediate of carbohydrate metabolism in certain organisms.
Synonym(s): pyruvic aldehyde

methylglyoxal

(mĕth″ĭl-glī-ŏk′sĭl, -awl)
An aldehyde formed from the metabolic degradation of glucose. Methylglyoxal can bind to proteins and DNA, causing metabolic damage to tissues (e.g., in diabetes mellitus), mutations, or cell death.
References in periodicals archive ?
It is also possible that L-GA inhibits glycolysis through autooxidation to methylglyoxal or pyruvaldehyde, which are known to form covalent adducts with proteins and to inhibit many cellular processes (15).