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Pyrogen

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pyrogen /py·ro·gen/ (pi´ro-jen) a fever-producing substance.

py·ro·gen (p

r

-j

n)

n.

A substance that produces a fever.

Pyrogen

A chemical circulating in the blood that causes a rise in body temperature.

Mentioned in: Fever

pyrogen

an agent that causes fever.

endogenous pyrogen (EP)

the mediator of fever, produced by polymorphonuclear leukocytes, monocytes and macrophages.

exogenous pyrogen

lipopolysaccharides and other substances produced by pathogenic microorganisms.

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Fever of Unknown Origin

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